中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [29]
采集方式
OAI收割 [29]
内容类型
期刊论文 [29]
发表日期
2017 [29]
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发表日期:2017
专题:上海药物研究所
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Discovery of a Potential Plasma Protein Biomarker Panel for Acute-on-Chronic Liver Failure Induced by Hepatitis B Virus
期刊论文
OAI收割
FRONTIERS IN PHYSIOLOGY, 2017, 卷号: 8
作者:
Zhou, Ni
;
Wang, Kuifeng
;
Fang, Shanhua
;
Zhao, Xiaoyu
;
Huang, Tingting
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
HBV-ACLF
CHB
iTRAQ
proteomics
biomarker
Discovery and structure-activity-relationship study of novel conformationally restricted indane analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5262-5266
作者:
Zheng, Qiangang
;
Tang, Shuai
;
Fu, Xianlei
;
Chen, Ziqi
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
IDH1 inhibitor
Indane amide
Structure-based rational design
Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336
作者:
Fu, Yan
;
Tang, Shuai
;
Su, Yi
;
Lan, Xiaojing
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Cyclin-dependent kinase
CDK inhibitor
Structure-activity relationship
In vitro and in vivo profiling
The miR-491-3p/Sp3/ABCB1 axis attenuates multidrug resistance of hepatocellular carcinoma
期刊论文
OAI收割
CANCER LETTERS, 2017, 卷号: 408, 页码: 102-111
作者:
Zhao, Yang
;
Qi, Xinming
;
Chen, Jing
;
Wei, Wenxin
;
Yu, Cunzhi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Hepatocellular carcinoma
ABCB1
Sp3
miR-491-3p
Multidrug resistance
Safety, Pharmacokinetics and Pharmacodynamics of Hetrombopag Olamine, a Novel TPO-R Agonist, in Healthy Individuals
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2017, 卷号: 121, 期号: 5, 页码: 414-422
作者:
Zheng, Li
;
Liang, Mao-zhi
;
Zeng, Xiao-ling
;
Li, Cai-zheng
;
Zhang, Yi-fan
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABA(A)alpha 1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference
期刊论文
OAI收割
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2017, 卷号: 10
作者:
Jiao, Dong-Liang
;
Chen, Yan
;
Liu, Yao
;
Ju, Yun-Yue
;
Long, Jian-Dong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
methamphetamine
GABA(A)alpha 1
dorsal striatum
ERAD
SYVN1
Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 598-611
作者:
Qian, Hai-Yan
;
Wang, Zhi-Long
;
Xie, Xiao-Yu
;
Pan, You-Lu
;
Li, Gang-Jian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Pyridazine-3-carboxamides
CB2 agonist
Structure-activity relationships
Molecular docking
logP
Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4701-4714
作者:
Yan, Jianwei
;
Wang, Gaihong
;
Dang, Xiangyu
;
Guo, Binbin
;
Chen, Wuhong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
DGAT-1
Inhibitor
Triglyceride
Hyperlipidemia
Amyloid beta: structure, biology and structure-based therapeutic development
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 9, 页码: 1205-1235
作者:
Chen, Guo-fang
;
Xu, Ting-hai
;
Yan, Yan
;
Zhou, Yu-ren
;
Jiang, Yi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
amyloid beta peptide
amyloid precursor protein
Alzheimer's disease
neurodegenerative diseases
drug discovery
Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 16, 页码: 7067-7083
作者:
Shi, Ying
;
Duan, Yan-Hui
;
Ji, Yue-Yang
;
Wang, Zhi-Long
;
Wu, Yan-Ran
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08