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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
采集方式
OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2019 [15]
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发表日期:2019
专题:上海药物研究所
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LysargiNase and Chemical Derivatization Based Strategy for Facilitating In-Depth Profiling of C-Terminome
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2019, 卷号: 91, 期号: 22, 页码: 14522-14529
作者:
Hu, Hao
;
Zhao, Wensi
;
Zhu, Mengdi
;
Zhao, Lei
;
Zhai, Linhui
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
Comparison of high-resolution synchrotron-radiation-based phase-contrast imaging and absorption-contrast imaging for evaluating microstructure of vascular networks in rat brain: from 2D to 3D views
期刊论文
OAI收割
JOURNAL OF SYNCHROTRON RADIATION, 2019, 卷号: 26, 页码: 2024-2032
作者:
Li, Hong-Lei
;
Ding, Hui
;
Yin, Xian-Zhen
;
Chen, Zhuo-Hui
;
Tang, Bin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
2D
3D
brain
microtomography
synchrotron radiation
vascular network
Peptide Nanotube-Templated Biomineralization of Cu2-xS Nanoparticles for Combination Treatment of Metastatic Tumor
期刊论文
OAI收割
SMALL, 2019, 页码: 13
作者:
Lai, Yi
;
Xu, Zhiai
;
Hu, Xianli
;
Lei, Li
;
Li, Lingling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
biomineralization
cancer metastasis
combination therapy
Fenton reaction
peptide nanotubes
fDiscovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 72-85
作者:
Zhan, Wenhu
;
Che, Jinxin
;
Xu, Lei
;
Wu, Yizhe
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Pyrazole-thiophene derivatives
Akt inhibitor
Antitumor
Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 15, 页码: 7264-7288
作者:
Dong, Xiaowu
;
Zhan, Wenhu
;
Zhao, Mengting
;
Che, Jinxin
;
Dai, Xiaoyang
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62
作者:
Tong, Lexian
;
Song, Pinrao
;
Jiang, Kailong
;
Xu, Lei
;
Jin, Tingting
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
CHK1 kinase inhibitor
Selectivity
Monotherapy
Hematologic malignancies
Bioinspired Multivalent Peptide Nanotubes for Sialic Acid Targeting and Imaging-Guided Treatment of Metastatic Melanoma
期刊论文
OAI收割
SMALL, 2019, 卷号: 15, 期号: 22, 页码: 11
作者:
Lei, Li
;
Xu, Zhiai
;
Hu, Xianli
;
Lai, Yi
;
Xu, Jie
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
combination therapy
imaging-guided treatment
multivalent targeting
peptide nanotubes
sialic acid
Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia
期刊论文
OAI收割
CANCER CELL, 2019, 卷号: 35, 期号: 4, 页码: 677-+
作者:
Huang, Yue
;
Su, Rui
;
Sheng, Yue
;
Dong, Lei
;
Dong, Ze
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
MiR-183-5p is required for non-small cell lung cancer progression by repressing PTEN
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 111, 页码: 1103-1111
作者:
Wang, Huimin
;
Ma, Zhongliang
;
Liu, Xiaomin
;
Zhang, Caiyan
;
Hu, Yanping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
miR-183-5p
Non-small cell lung cancer
PTEN
Tumorigenesis
Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 602-614
作者:
Dong, Xiao-Wu
;
Zhang, Jian-Kang
;
Xu, Lei
;
Che, Jin-Xin
;
Cheng, Gang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Proteasome inhibitors
Tripeptide
Covalent docking
Interaction mode