中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2020 [14]
学科主题
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发表日期:2020
专题:上海药物研究所
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Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 6
作者:
Hu, Wen-juan
;
Chang, Lu
;
Yang, Ying
;
Wang, Xin
;
Xie, Yuan-chao
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/12/21
remdesivir
pharmacokinetics
tissue distribution
nucleotide monophosphate
nucleotide triphosphate
nucleoside
The design of a novel near-infrared fluorescent HDAC inhibitor and image of tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 卷号: 28, 期号: 17, 页码: 5
作者:
Huang, Ying
;
Ru, Hong-bo
;
Bao, Bin
;
Yu, Jia-hui
;
Li, Jia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/12/24
HDAC
Probe
NIR
Tumor imaging
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe
期刊论文
OAI收割
Journal of Experimental & Clinical Cancer Research, 2020, 卷号: 39, 期号: 1
作者:
Hu,Liangning
;
Li,Bo
;
Chen,Gege
;
Song,Dongliang
;
Xu,Zhijian
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/07/01
Multiple myeloma
Drug-resistance
DNA damage response
Cell cycle
A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib
期刊论文
OAI收割
CANCER LETTERS, 2020, 卷号: 478, 页码: 45-55
作者:
Chen, Gege
;
Hu, Ke
;
Sun, Haiguo
;
Zhou, Jinfeng
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Multiple myeloma
Bone marrow microenvironment
DNA damage
JAK2/STAT3 pathway
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins
Design and synthesis of new lenalidomide analogs via Suzuki cross-coupling reaction
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2020, 页码: 10
作者:
Xiao, Donghuai
;
Wang, Yu-jie
;
Wang, Han-lin
;
Zhou, Yu-bo
;
Li, Jia
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
antitumor
arylboronic acid
lenalidomide
Suzuki cross-coupling
A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 卷号: 5, 期号: 1, 页码: 11
作者:
Lu, Kang
;
Li, Bo
;
Zhang, Hui
;
Xu, Zhijian
;
Song, Dongliang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Synchrotron Radiation-Based Three-Dimensional Visualization of Angioarchitectural Remodeling in Hippocampus of Epileptic Rats
期刊论文
OAI收割
NEUROSCIENCE BULLETIN, 2020, 卷号: 36, 期号: 4, 页码: 333-345
作者:
Gu, Pan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Epilepsy
Synchrotron radiation
3D
Angioarchitecture
Blood vessel
Remodeling
Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2020, 卷号: 52, 期号: 4, 页码: 401-410
作者:
Xi, Mengyu
;
He, Wan
;
Li, Bo
;
Zhou, Jinfeng
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DCZ0801
DLBCL
apoptosis
cell cycle
MAPK