中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
机构
  • 上海药物研究所 [90]
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内容类型
发表日期
  • 2020 [90]
学科主题
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A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP-Protein Interactions in Kidney Cancer Cells 期刊论文  OAI收割
CHINESE JOURNAL OF CHEMISTRY, 2020, 页码: 274-280
作者:  
Wang, Zhen;  Zhang, Hao;  Chen, Baoen;  Ouyang, Sisheng;  Zheng, Tong
  |  收藏  |  浏览/下载:123/0  |  提交时间:2021/05/24
Substitution Effect of the Trifluoromethyl Group on the Bioactivity in Medicinal Chemistry: Statistical Analysis and Energy Calculations 期刊论文  OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2020, 卷号: 60, 期号: 12, 页码: 6242-6250
作者:  
Abula, Amina;  Xu, Zhijian;  Zhu, Zhengdan;  Peng, Cheng;  Chen, Zhaoqiang
  |  收藏  |  浏览/下载:24/0  |  提交时间:2021/05/24
Computational Insights into the Conformational Accessibility and Binding Strength of SARS-CoV-2 Spike Protein to Human Angiotensin-Converting Enzyme 2 期刊论文  OAI收割
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2020, 卷号: 11, 期号: 24, 页码: 10482-10488
作者:  
Peng, Cheng;  Zhu, Zhengdan;  Shi, Yulong;  Wang, Xiaoyu;  Mu, Kaijie
  |  收藏  |  浏览/下载:28/0  |  提交时间:2021/05/24
Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文  OAI收割
CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24
作者:  
Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang
  |  收藏  |  浏览/下载:75/0  |  提交时间:2021/05/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  
Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan
  |  收藏  |  浏览/下载:95/0  |  提交时间:2020/12/24
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:  
Bi, Xiaoyang;  Chen, Yu;  Sun, Zhongya;  Lu, Wenchao;  Xu, Pan
  |  收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:  
Zhang, Bin;  Liao, Liping;  Wu, Fan;  Zhang, Fengcai;  Sun, Zhongya
  |  收藏  |  浏览/下载:36/0  |  提交时间:2021/05/24
Epigenetics 2.0: Special Issue on Epigenetics-Call for Papers 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12129-12130
作者:  
Conway, Stuart J.;  Arimondo, Paola;  Arrowsmith, Cheryl;  Jin, Jian;  Luo, Cheng
  |  收藏  |  浏览/下载:9/0  |  提交时间:2021/05/24
Therapy for Apnoea of Prematurity: A Retrospective Study on Effects of Standard Dose and Genetic Variability on Clinical Response to Caffeine Citrate in Chinese Preterm Infants 期刊论文  OAI收割
ADVANCES IN THERAPY, 2020, 页码: 20
作者:  
He, Xin;  Qiu, Jin-Chun;  Lu, Ke-Yu;  Guo, Hong-Li;  Li, Ling
  |  收藏  |  浏览/下载:31/0  |  提交时间:2020/12/24
Transcriptional and proteomic insights into the host response in fatal COVID-19 cases 期刊论文  OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 45, 页码: 28336-28343
作者:  
Wu, Meng;  Chen, Yaobing;  Xia, Han;  Wang, Changli;  Tan, Chin Yee
  |  收藏  |  浏览/下载:54/0  |  提交时间:2020/12/24