中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
采集方式
OAI收割 [14]
内容类型
期刊论文 [14]
发表日期
2023 [14]
学科主题
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浏览/检索结果:
共14条,第1-10条
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发表日期:2023
专题:上海药物研究所
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Design, synthesis and biological evaluation of chalcone derivatives as potent and orally active hCYP3A4 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 9
作者:
Lu, Shiwei
;
Zhang, Feng
;
Gong, Jiahao
;
Huang, Jian
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/08
Cytochrome P450 3A4 (CYP3A4)
Inhibitors
Isoquinoline chalcones
Orally active
Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
期刊论文
OAI收割
CELL METABOLISM, 2023, 卷号: 35, 期号: 10, 页码: 1752-+
作者:
Kuang, Junliang
;
Wang, Jieyi
;
Li, Yitao
;
Li, Mengci
;
Zhao, Mingliang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
Highly Modified Sesquiterpene Lactones with Cytotoxic Activities from Strobocalyx chunii
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 88, 期号: 15, 页码: 11122-11129
作者:
Ge, Zhan-Peng
;
Gao, Yuan
;
Zhang, Yan
;
Liu, Hong-Chun
;
Zhao, Jin-Xin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
The heparan sulfate mimetic Muparfostat aggravates steatohepatitis in obese mice due to its binding affinity to lipoprotein lipase
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2023, 卷号: 180, 期号: 14, 页码: 1803-1818
作者:
Zhang, Jia
;
Li, Kai
;
Sun, Hao-Ran
;
Sun, Shao-Kun
;
Zhu, Ya-Ting
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
heparan sulfate mimetic
heparanase inhibitor
hepatic steatosis
lipoprotein lipase
obesity
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity
Cancer-Associated Fibroblast-Derived miR-146a-5p Generates a Niche That Promotes Bladder Cancer Stemness and Chemoresistance
期刊论文
OAI收割
CANCER RESEARCH, 2023, 卷号: 83, 期号: 10, 页码: 1611-1627
作者:
Zhuang, Junlong
;
Shen, Lan
;
Li, Meiqian
;
Sun, Jingya
;
Hao, Jiange
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Shape and Shear Stress Impact on the Toxicity of Mesoporous Silica Nanoparticles: In Vitro and In Vivo Evidence
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2023, 卷号: 20, 期号: 6, 页码: 3187-3201
作者:
Cheng, Yaxin
;
Tao, Jinsong
;
Zhang, Yaqi
;
Xi, Long
;
Han, Run
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
mesoporous silica nanoparticles (MSNs)
toxicity
shape
shear stress
in vitro blood flow model
Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 5, 页码: 2384-2391
作者:
Xu, Zhijian
;
Shi, Danrong
;
Han, Jianbao
;
Ling, Yun
;
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/27
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 153
作者:
Zhang, Xu
;
Wang, Yuxiang
;
Zhang, Xi
;
Shen, Yanyan
;
Yang, Kang
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/03/27