机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2024 [4]
• 2023 [4]
• 2022 [4]
• 2020 [1]

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 限定条件 内容类型：期刊论文    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 A validated LC-MS/MS method for the quantitation of daratumumab in rat serum using rapid tryptic digestion without IgG purification and reduction 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 243, 页码: 8 作者:  Li, Weiqiang;  Huang, Wensi;  Yu, Xiong;  Chen, Chong;  Yuan, Yali   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/22 Daratumumab  LC-MS/MS  Surrogate peptide  Pharmacokinetics   Pharmacokinetics, mass balance, and metabolism of [14C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects 期刊论文  OAI收割 CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 页码: 11 作者:  Ma, Sheng;  Wang, Xin;  Yan, Shu;  Miao, Liyan;  Wan, Xiaojing   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/05/07 Envonalkib  TQ-B3139  Pharmacokinetics  Mass balance  Excretion  Metabolism   Discovery of Pyrido[2,3-d]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006 作者:  Sun, Yaoliang;  Chen, Manman;  Han, Yuyan;  Li, Weiqiang;  Ma, Xiaoyu   |  收藏  |  浏览/下载：1/0  |  提交时间：2024/05/07 Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS 期刊论文  OAI收割 XENOBIOTICA, 2024, 页码: 9 作者:  Yuan, Yali;  Wang, Weiqiang;  Luo, Jing;  Tang, Chongzhuang;  Zheng, Yuandong   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/19 peptide-drug conjugate  PDC  LN005  metabolite identification  liver S9s   A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11 作者:  Zhou, Ainan;  Yu, Jinghua;  Wu, Yali;  Xue, Hao;  Zhong, Dafang   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Monoclonal antibody  Bevacizumab  LC-MS  MS  Surrogate peptide  Pharmacokinetics  Serum   Discovery and Structural Optimization of Covalent ZAP-70 Kinase Inhibitors against Psoriasis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15 作者:  Rao, Danni;  Yang, Tao;  Feng, Huixu;  An, Qi;  Zhang, Shaofeng   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Wu, Feifei;  Li, Huiyu;  An, Qi;  Sun, Yaoliang;  Yu, Jinghua   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Hematopoietic progenitor kinase 1 (HPK1)  Cancer immunotherapy  Inhibitor  T cell   Pharmacokinetics,mass balance,and metabolism of 14C TPN171,a novel PDE5 inhibitor,in humans for the treatment of pulmonary arterial hypertension 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 1, 页码: 221 作者:  He Yifei;  Liu Yin   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/05/22 TPN171  14CTPN171  PDE5 inhibitor  pulmonary arterial hypertension  healthy volunteers  pharmacokinetics  metabolite identification  mass balance   A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1 beta and IL-6 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 11, 页码: 4180-4192 作者:  Liao, Liping;  Dang, Wenzhen;  Lin, Tingting;  Yu, Jinghua;  Liu, Tonghai   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Glycolysis  Phosphoglycerate kinase 1  Macrophages  NRF2  Inflammation   Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2022, 卷号: 50, 期号: 6, 页码: 809-818 作者:  Guo, Zitao;  Liu, Mengling;  Meng, Jian;  Xue, Yaru;  Huang, Qi   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/08/16