中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
采集方式
OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2023 [2]
2022 [4]
2021 [8]
2018 [4]
2017 [2]
2016 [1]
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专题:上海药物研究所
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HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production
期刊论文
OAI收割
FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12
作者:
Kong, Xiangrong
;
Liu, Wei
;
Zhang, Xinwen
;
Zhou, Chendong
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
acute liver failure
cell death
HIF-1 alpha inhibitor
interleukin-1 beta
macrophage
Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 2, 页码: 112033
作者:
He, Yuman
;
Ji, Zhongzhong
;
Gong, Yiming
;
Fan, Liancheng
;
Xu, Penghui
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9
作者:
Hart, Jonathan R.
;
Liu, Xiao
;
Pan, Chen
;
Liang, Anyi
;
Ueno, Lynn
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
phosphoinositide 3-kinase (PI3K)
nanobody
conformational changes
chemical cross-linking
mass spectrometry
BPTF inhibition antagonizes colorectal cancer progression by transcriptionally inactivating Cdc25A
期刊论文
OAI收割
REDOX BIOLOGY, 2022, 卷号: 55, 页码: 16
作者:
Guo, Ping
;
Zu, Shijia
;
Han, Shilong
;
Yu, Wendan
;
Xue, Guoqing
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/12/13
Colorectal cancer
BPTF
Cdc25A
c-Myc
Cell cycle
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
;
Bao, Ruoxuan
;
Guo, Xiaozhen
;
Gu, Yuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer
Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Zhao, Fenghui
;
Zhou, Qingtong
;
Cong, Zhaotong
;
Hang, Kaini
;
Zou, Xinyu
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2022/06/15
Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence
期刊论文
OAI收割
NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089
作者:
Bai, Xiangd
;
Wang, Hanchen
;
Ma, Liya
;
Xu, Yongchao
;
Gan, Jiefeng
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2022/01/18
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:
Liu, Xiao
;
Yang, Su
;
Hart, Jonathan R.
;
Xu, Yingna
;
Zou, Xinyu
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2022/01/04
phosphoinositide 3-kinase (PI3K)
activation
inhibition
activity-dependent conformational changes
Constitutive signal bias mediated by the human GHRHR splice variant 1
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10
作者:
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/12/01
class B1 GPCR
receptor bias
cancer
cell proliferation
Gut Microbiota in Adipose Tissue Dysfunction Induced Cardiovascular Disease: Role as a Metabolic Organ
期刊论文
OAI收割
FRONTIERS IN ENDOCRINOLOGY, 2021, 卷号: 12, 页码: 14
作者:
Yang, Xinyu
;
Zhang, Xianfeng
;
Yang, Wei
;
Yu, Hang
;
He, Qianyan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/11/04
gut microbiota
adipose tissue dysfunction
molecular endocrinology
cardiovascular disease(s)
gut dysbiosis