中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [106]
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Low molecular weight fucoidan restores diabetic endothelial glycocalyx by targeting neuraminidase2: A new therapy target in glycocalyx shedding
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2024, 页码: 17
作者:
Li, Zhi
;
Wu, Ning
;
Wang, Jing
;
Yue, Yang
;
Geng, Lihua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/04/07
diabetic vascular complication
glycocalyx
insulin resistance
LMWF
NEU2
Delving the Role of the Ameliorative Effects of
Caralluma tuberculata
NEBr. (Apocynaceae) on Diabetes and Its Effect on the Organs Weight of Alloxan-Induced Adult Male Mice
期刊论文
OAI收割
POLISH JOURNAL OF ENVIRONMENTAL STUDIES, 2024, 卷号: 33, 期号: 1, 页码: 523-531
作者:
Batool, Saira
;
Batool, Sajida
;
Batool, Tahira
;
Iram, Fatima
;
Almas, Tahira
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/01
alloxan
ameliorative effects
Caralluma tuberculata
diabetes
hypoglycemic effects
Paired box 6 gene delivery preserves beta cells and improves islet transplantation efficacy
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 20
作者:
So, Wing Yan
;
Liao, Yilie
;
Liu, Wai Nam
;
Rutter, Guy A.
;
Han, Weiping
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/11
AAV
beta cells
diabetes
islet transplant
PAX6
Anxiolytic effect of antidiabetic metformin is mediated by AMPK activation in mPFC inhibitory neurons
期刊论文
OAI收割
MOLECULAR PSYCHIATRY, 2023, 页码: 11
作者:
Zhang, Yong-mei
;
Zong, Hai-chao
;
Qi, Ying-bei
;
Chang, Liu-liu
;
Gao, Ya-nan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/12/08
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
OAI收割
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
Magnesium lithospermate B ameliorates diabetic nephropathy by suppressing the uremic toxin formation mediated by gut microbiota
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 953, 页码: 12
作者:
Zhu, Nanlin
;
Duan, Haonan
;
Feng, Yingying
;
Xu, Wenwei
;
Shen, Jianhua
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
Diabetic nephropathy
Magnesium lithospermate B
Gut microbiota
Uremic toxins
p -Cresyl sulfate metabolism
Pharmacokinetics of fucoidan and low molecular weight fucoidan from Saccharina japonica after oral administration to mice
期刊论文
OAI收割
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2023, 页码: 10
作者:
Tan, Jiaojiao
;
Song, Yimin
;
Wang, Jing
;
Wu, Ning
;
Yue, Yang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2023/12/13
fucoidan
low molecular weight fucoidan
pharmacokinetics
bioavailability
tissue distribution
Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
OAI收割
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
Multi-omics analysis reveals the pathogenesis of db/db mice diabetic kidney disease and the treatment mechanisms of multi-bioactive compounds combination from Salvia miltiorrhiza
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 16
作者:
Xu, Zhuo
;
Xiang, Xiang
;
Su, Shulan
;
Zhu, Yue
;
Yan, Hui
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/13
multi-bioactive compounds combination
diabetic kidney disease
multi-omics
Salvia miltiorrhiza
PI3K/Akt/FoxO signaling pathways
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships