中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果:
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Reversible SAHH inhibitor ameliorates MIA-induced osteoarthritis of rats through suppressing MEK/ERK pathway
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2024, 卷号: 170, 页码: 6
作者:
Fan, Shu-Hui
;
Chang, Yuan
;
Xiong, Xiao-Yu
;
Xiang, Mai
;
Yuan, Wen-Long
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/27
DZ2002
Osteoarthritis
Osteoclast
Bone resorption
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:
Zhang, Jingni
;
Wang, Hongjuan
;
Chen, Huan
;
Liu, Yong
;
Wang, An
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/11/17
Acetaldehyde
Cytotoxicity
Genotoxicity
BEAS-2B cells
HHSteCs
MAPK/ERK
PI3K/AKT
Design, synthesis and biological evaluation of KRASG12C-PROTACs
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14
作者:
Zhang, Xiaoyi
;
Zhao, Tong
;
Sun, Minghao
;
Li, Pei
;
Lai, Mengzhen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10
KRASG12C
PROTAC
Covalent inhibitors
Structure-activity relationships (SARs)
Anticancer
Design, Synthesis, and Bioevaluation of Pyrido[2,3-d]pyrimidin-7-ones as Potent SOS1 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2023, 页码: 183-190
作者:
Liu, Meiying
;
Zhou, Guizhen
;
Su, Wenhong
;
Gu, Yuejiao
;
Gao, Mingshan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/27
KRAS mutation
SOS1-KRAS interaction
SOS1 inhibitor
combination therapy
The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization
DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2022, 卷号: 12, 期号: 1, 页码: 15
作者:
Zhang, Huiying
;
Li, Bo
;
Ding, Jingjuan
;
Ye, Rong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
期刊论文
OAI收割
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2022, 卷号: 11, 期号: 12, 页码: 15
作者:
Ding, Jingjuan
;
Li, Bo
;
Zhang, Huiying
;
Xu, Zhijian
;
Zhang, Qiuyang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/10/17
ocular neovascularization
DCZ19903
multitarget kinase inhibitor
network pharmacology
MAPK signaling pathway
A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling
期刊论文
OAI收割
GLYCOCONJUGATE JOURNAL, 2022, 页码: 11
作者:
Liao, Wenfeng
;
Hu, Xiaodong
;
Du, Zhenyun
;
Wang, Peipei
;
Ding, Kan
  |  
收藏
  |  
浏览/下载:105/0
  |  
提交时间:2022/12/13
Homogalacturonan
Angiogenesis
Lonicera japonica
EGFR/Raf/MEK/ERK signaling cascade
Dll4/Notch1 signaling