中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486
作者:
Chang, Qi
;
Li, Jiayi
;
Deng, Yue
;
Zhou, Ruilin
;
Wang, Bingwei
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/25
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
OAI收割
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
SEPepQuant enhances the detection of possible isoform regulations in shotgun proteomics
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Dou, Yongchao
;
Liu, Yuejia
;
Yi, Xinpei
;
Olsen, Lindsey K.
;
Zhu, Hongwen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388
作者:
Dou, Wei-Tao
;
Qiu, Peng
;
Shi, Yuanyuan
;
Zhu, Ling
;
Guo, Chen
  |  
收藏
  |  
浏览/下载:238/0
  |  
提交时间:2023/10/17
Dominant neoantigen verification in hepatocellular carcinoma by a single-plasmid system coexpressing patient HLA and antigen
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 卷号: 11, 期号: 4, 页码: 16
作者:
Chen, Pu
;
Chen, Dongbo
;
Bu, Dechao
;
Gao, Jie
;
Qin, Wanying
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/04
Liver Neoplasms
Antigens
Neoplasm
Immunotherapy
Immunoassay
Immunogenicity
Vaccine
Enhanced glypican-3-targeted identification of hepatocellular carcinoma with liver fibrosis by pre-degrading excess fibrotic collagen
期刊论文
OAI收割
Acta Biomaterialia, 2023, 卷号: 158, 页码: 435- 448
作者:
Zhuo, Jiaming
;
Wang, Yueqi
;
Hui, Hui
;
Li, Changjian
;
Yang, Junying
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/05/04
Cytotoxic and pro-apoptotic effects of botanical drugs derived from the indigenous cultivated medicinal plant Paris polyphylla var. yunnanensis
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1100825
作者:
Yan,Xiu-Xiang
;
Zhao,Yan-Qiang
;
He,Yun
;
Disayathanoowat,Terd
;
Pandith,Hataichanok
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/09
Paris polyphylla var
yunnanensis
indigenous medicine knowledge
saponins
cytotoxic effects
pro-apoptotic effects
CELL-CYCLE ARREST
STEROIDAL SAPONINS
HEPATOCELLULAR-CARCINOMA
CHEMICAL-CONSTITUENTS
ASSAY
GLYCOSIDES
LEAVES
GROWTH
STEMS
SITES
Artemongolins A-K, undescribed germacrane-guaiane sesquiterpenoid dimers from Artemisia mongolica and their antihepatoma activities
期刊论文
OAI收割
ARCHIVES OF PHARMACAL RESEARCH, 2023, 卷号: 46, 期号: 9-10, 页码: 782-794
作者:
Shang,Chong
;
Ma,Yun-Bao
;
Wang,Yuan
;
He,Xiao-Feng
;
Li,Tian-Ze
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/09
Artemisia mongolica
Artemongolins A-K
Sesquiterpenoid dimers
Antihepatoma activity
HEPATOCELLULAR-CARCINOMA
LACTONE
ARGYI
The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1
期刊论文
OAI收割
ONCOGENE, 2022, 卷号: 41, 期号: 33, 页码: 4018-4027
作者:
Gao, Ming
;
Qi, Zijuan
;
Deng, Min
;
Huang, Hongyang
;
Xu, Zhijie
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/11/08
HEME OXYGENASE-1
ARSENIC TOXICITY
UBIQUITINATION
USP7/HAUSP
ACTIVATION
MECHANISMS
CANCER
NRF2
P53
Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466
作者:
Sun, Renqiang
;
Zhang, Zhiyong
;
Bao, Ruoxuan
;
Guo, Xiaozhen
;
Gu, Yuan
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/03/21
SIRT5
bile acid
macrophage polarization
immunosuppressive tumor microenvironment
liver cancer