中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [92]
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期刊论文 [564]
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Structurally diverse terpenoids and their DRAK2 inhibitory activities: A follow-up study on the vulnerable conifer Pseudotsuga forrestii
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1305, 页码: 13
作者:
Zhou, Peng-Jun
;
Huang, Ting
;
Ma, Guang-Lei
;
Zhao, Ze-Yu
;
Jiang, Zhe-Lu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Pseudotsuga forrestii
Rare and endangered plants (REPs)
Triterpene-monoterpene hybrids
GLMDs
DRAK2 inhibition
Molecular docking
Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035
作者:
Shi, Yunkai
;
Liu, Minmin
;
Li, Mengna
;
Mao, Yiwen
;
Ma, Jingkun
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/05/07
RIPK1 inhibitor ameliorates pulmonary injury by modulating the function of neutrophils and vascular endothelial cells
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 12
作者:
Yang, Tao
;
Xiang, Cai-gui
;
Wang, Xiao-han
;
Li, Qing-qing
;
Lei, Shu-yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Molecular Insights into O-Linked Sialoglycans Recognition by the Siglec-Like SLBR-N (SLBR
UB10712
) of Streptococcus gordonii
期刊论文
OAI收割
ACS CENTRAL SCIENCE, 2024, 卷号: 10, 期号: 2, 页码: 447-459
作者:
Di Carluccio, Cristina
;
Cerofolini, Linda
;
Moreira, Miguel
;
Rosu, Frederic
;
Padilla-Cortes, Luis
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
ABHD6 drives endocytosis of AMPA receptors to regulate synaptic plasticity and learning flexibility
期刊论文
OAI收割
PROGRESS IN NEUROBIOLOGY, 2024, 卷号: 233, 页码: 17
作者:
Wei, Mengping
;
Yang, Lei
;
Su, Feng
;
Liu, Ying
;
Zhao, Xinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/25
AMPA receptors
ABHD6
Endocytosis
Synaptic plasticity
Learning flexibility
LncRNA pol-lnc78 as a ceRNA regulates antibacterial responses via suppression of pol-miR-n199-3p-mediated SARM down-regulation in Paralichthys olivaceus
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45, 期号: 1, 页码: 25-35
作者:
Ning, Xian-Hui
;
Han, Bing
;
Peng, Ye
;
Yin, Shao-Wu
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/07
LncRNA
SARM
miRNA
ceRNA
Antibacterial response
Paralichthys olivaceus
MLKL-mediated necroptosis is activated by RIPK1/3 and involved in anti-microbial immunity
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 11
作者:
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/07
Paralichthys olivaceus
necroptosis
RIPK1
RIPK3
MLKL
immune defense
Structure-based development of potent and selective type-II kinase inhibitors of RIPK1
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 1, 页码: 319-334
作者:
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/06
RIPK1
Necroptosis
Type-II kinase inhibitors
Rational design
Lead optimization
Structure-activity relationship
Anti-inflammation
Preclinical drug discovery
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08