中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Functional analyses of TRAF6 gene in Argopecten scallops
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 147, 页码: 9
作者:
Zhang, Xiaotong
;
Wang, Xia
;
Chen, Jieyu
;
Chen, Min
;
Lu, Xia
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Argopecten irradians (Air)
Argopecten purpuratus (Apu)
Tumor necrosis factor (TNF)
TNF receptor-associated factor (TRAF)
Subcellular localization
RNA interference (RNAi)
Complex
N
-glycans are important for interspecies transmission of H7 influenza A viruses
期刊论文
OAI收割
JOURNAL OF VIROLOGY, 2024, 页码: 21
作者:
Spruit, Cindy M.
;
Palme, Diana I.
;
Li, Tiehai
;
Rios Carrasco, Maria
;
Gabarroca Garcia, Alba
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
influenza A virus
hemagglutinin
interspecies transmission
sialyl-LewisX
NeuGc
Adenosine-modulating synthetic high-density lipoprotein for chemoimmunotherapy of triple-negative breast cancer
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 367, 页码: 637-648
作者:
Gong, Xiang
;
Zheng, Chao
;
Cai, Ying
;
Zhang, Wen
;
Zhu, Binyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Peptide-drug conjugate
Synthetic high-density lipoprotein
Adenosine
Immunogenic cell death
Immunosuppression
JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers
期刊论文
OAI收割
CANCER LETTERS, 2024, 卷号: 582, 页码: 15
作者:
Lu, Xuxiu
;
Yu, Rilei
;
Li, Zhen
;
Yang, Mengke
;
Dai, Jiajia
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/04/07
Acquired resistance
Cancer
NSCLC
JC-010a
SHP2
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:
Feng, Dazhi
;
Liu, Bo
;
Chen, Zhiwei
;
Xu, Jinyi
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/02/27
HPK1 inhibitor
machine learning
virtual screening
free energy perturbation
structural modification
Tumor-Associated Macrophage Targeting of Nanomedicines in Cancer Therapy
期刊论文
OAI收割
PHARMACEUTICS, 2024, 卷号: 16, 期号: 1, 页码: 28
作者:
Kang, Xuejia
;
Huang, Yongzhuo
;
Wang, Huiyuan
;
Jadhav, Sanika
;
Yue, Zongliang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
tumor-associated macrophage
suppressive immune environment
tumor proliferation and metastasis
nanomedicine
targeted delivery systems
Synthesis, evaluation and molecular dynamics study of human toll-like receptor 2/6 specific monoacyl lipopeptides as candidate immunostimulants
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 141, 页码: 17
作者:
Zhu, Yueyue
;
Liu, Bo
;
Chen, Zonglong
;
Wang, Xianyang
;
Wang, Yujie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Toll -like receptor 2/6 agonists
PamCS
Structure-activity relationship
Lipopeptide
Immunostimulants
Design, Synthesis, and Pharmacological Evaluation of Isoindoline Analogues as New HPK1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 23, 页码: 16201-16221
作者:
Xie, Chenghu
;
Liu, Bo
;
Song, Zilan
;
Yang, Ye
;
Dai, Mengdi
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 7
作者:
Zhu, Xiao
;
Gong, Likun
;
Qin, Qiuping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Antibody-dependent cell-mediated cytotoxicity
Time-resolved fluorescence
Monoclonal antibody
Antibody-Drug Conjugate
Eu
NK-92 cells