中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [169]
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半导体材料 [38]
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Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures
期刊论文
OAI收割
PLATELETS, 2024, 卷号: 35, 期号: 1, 页码: 9
作者:
Yang, Caiting
;
Han, Jie
;
Liu, Hai
;
He, Yuyu
;
Zhang, Zhenhua
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/21
exosome
anticoagulant
plasma
temperature
duration
Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Integrated multi-omics analysis reveals gut microbiota dysbiosis and systemic disturbance in major depressive disorder
期刊论文
OAI收割
PSYCHIATRY RESEARCH, 2024, 卷号: 334, 页码: 12
作者:
Xie, Zuoquan
;
Huang, Jingjing
;
Sun, Guangqiang
;
He, Shen
;
Luo, Zhiyu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/22
Major depressive disorder
Peripheral changes
Gut microbiota
Immune phenotyping
Multiomics
Biomarkers
Pharmacokinetics, mass balance, and metabolism of [
14
C]envonalkib (TQ-B3139), a novel ALK tyrosine kinase inhibitor, in healthy Chinese subjects
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 页码: 11
作者:
Ma, Sheng
;
Wang, Xin
;
Yan, Shu
;
Miao, Liyan
;
Wan, Xiaojing
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Envonalkib
TQ-B3139
Pharmacokinetics
Mass balance
Excretion
Metabolism
Pharmacokinetics and metabolite identification of 23-hydroxybetulinic acid in rats by using liquid chromatography-mass spectrometry method
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2024, 卷号: 1234, 页码: 10
作者:
Xue, Mingzhen
;
Yang, Cheng
;
Huang, Wensi
;
He, Yifei
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
23-hydroxybetulinic acid
Pharmacokinetics
Metabolism
UPLC-MS
LC-MS/MS
Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
Development of
in situ
Li isotope analysis using laser ablation quadrupole inductively coupled plasma mass spectrometry
期刊论文
OAI收割
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2024, 卷号: 38, 期号: 2, 页码: 7
作者:
Fan, Xuefei
;
Sio, Corliss Kin, I
;
Chu, Xu
;
Jiang, Hehe
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/02
Metabolism investigation of the peptide-drug conjugate LN005 in rats using UHPLC-HRMS
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2024, 卷号: 238, 页码: 11
作者:
Wang, Weiqiang
;
Chen, Chong
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/01/16
LN005
Metabolism
Peptide -drug conjugates
UHPLC-HRMS
Doxorubicin
Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of
Epimedium
and
Psoraleae Fructus
herb pair after oral administration
期刊论文
OAI收割
JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17
作者:
Wang, Linwei
;
Yin, Xiaoying
;
Liu, Huan
;
Wang, Yangyang
;
Li, Zhixiong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/02/27
compatibility behaviors
Epimedium
LC-MS/MS
pharmacokinetics
Psoraleae Fructus
Qing-Zhi-Tiao-Gan-Tang (QZTGT) prevents nonalcoholic steatohepatitis (NASH) by expression pattern correction
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 317, 页码: 14
作者:
Chu, Hang
;
Zhang, Weitao
;
Tan, Yan
;
Diao, Zhipeng
;
Li, Peng
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
Fibrosis
Inflammation
Lipogenesis
NASH
QZTGT
TMNP