中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of novel SOS1 inhibitors using machine learning
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 4, 页码: 1392-1403
作者:
Duo, Lihui
;
Chen, Yi
;
Liu, Qiupei
;
Ma, Zhangyi
;
Farjudian, Amin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Recent Progress of Small Interfering RNA Delivery on the Market and Clinical Stage
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2024, 页码: 16
作者:
Guo, Fan
;
Li, Yan
;
Yu, Wenjun
;
Fu, Yuanlei
;
Zhang, Jing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/22
gene therapy
small interfering RNAs
deliveryplatforms
hepatic targeting
extrahepatic targeting
Discovery of YFJ-36: Design, Synthesis, and Antibacterial Activities of Catechol-Conjugated β-Lactams against Gram-Negative Bacteria
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Liu, Fangjun
;
Kou, Qunhuan
;
Li, Hongyuan
;
Cao, Yangzhi
;
Chen, Meng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
Regulation of hippo signaling mediated apoptosis by
Rauvolfia tetraphylla
in triple-negative breast cancer
期刊论文
OAI收割
MEDICAL ONCOLOGY, 2024, 卷号: 41, 期号: 5, 页码: 14
作者:
Balavaishnavi, B.
;
Kamaraj, M.
;
Nithya, T. G.
;
Santhosh, P.
;
Gokilalakshmi, S.
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Anti-proliferative effect
Hippo pathway
MDA-MB-231 cells
Apoptosis
Rauvolfia tetraphylla
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/05/07
Discovery of potent PROTAC degraders of Pin1 for the treatment of acute myeloid leukemia
期刊论文
OAI收割
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 13, 页码: 5027-5035
作者:
Shi, Yunkai
;
Liu, Minmin
;
Li, Mengna
;
Mao, Yiwen
;
Ma, Jingkun
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/05/07
Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4560-4582
作者:
Yang, Guan-Zhou
;
Wang, Lei
;
Gao, Kun
;
Zhu, Xi
;
Lou, Li-Guang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
Prevalence and risk factors for abnormal glucose metabolism in first-episode and drug-na?ve major depressive disorder outpatients with comorbid anxiety: A cross-sectional study from a large sample of the Chinese Han population
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 349, 页码: 400-406
作者:
Xu, Huixue
;
Liu, Liyan
;
Yang, Qian
;
Wang, Xin
;
Li, Zejun
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/25
Major depressive disorder
Glucose disturbances
First -episode drug-naive
Anxiety
Dehydrocurvularin-loaded mPEG-PLGA nanoparticles for targeted breast cancer drug delivery: preparation, characterization,
in vitro
, and
in vivo
evaluation
期刊论文
OAI收割
JOURNAL OF DRUG TARGETING, 2024, 卷号: 32, 期号: 3, 页码: 325-333
作者:
Cui, Xuewei
;
He, Zhong
;
Liang, Jianjia
;
Wei, Mulan
;
Guo, Zhiyong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/06
Dehydrocurvularin
nanoparticles
breast cancer
solubility
tumour targeting
Chemical Space Profiling of SARS-CoV-2 PL
pro
Using DNA-Encoded Focused Libraries
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 10
作者:
Wang, Xudong
;
Zhu, Ying
;
Zhao, Qingyi
;
Lu, Weiwei
;
Xu, Yechun
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/05/07
DNA-Encoded Focused Libraries (DEFLs)
SARS-CoV-2
Papain-like Protease
Library Design
ProteinInhibitors