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Chinese Academy of Sciences Institutional Repositories Grid
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Pharmacokinetics, mass balance, and metabolism of [
14
C]PLB1004, a selective and irreversible EGFR-TKI in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14
作者:
Liu, Donghui
;
Li, Qian
;
Yan, Shu
;
Zhang, Xinyue
;
Li, Weiqiang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/04/01
PLB1004
[C-14]PLB1004
Radioactivity
Mass balance
EGFR-TKI
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
Environmental thresholds triggering changes in above and belowground biomass carbon in China
期刊论文
OAI收割
GLOBAL ECOLOGY AND CONSERVATION, 2025, 卷号: 61, 页码: 18
作者:
Zhang, Xin
;
Zhang, Shihang
;
Zhou, Jun
;
Fan, Jianrong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/18
Aboveground biomass carbon
Belowground biomass carbon
Environmental factors
SSP5-8.5 scenarios
Spatial analysis
Climate change
Enhanced carbon sequestration in marginal seas through bacterial transformation
期刊论文
OAI收割
WATER RESEARCH, 2025, 卷号: 281, 页码: 7
作者:
Guo, Jinqiang
;
Zhou, Bu
;
Achterberg, Eric P.
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/07/11
Particulate organic matter
Amino acids
Bacterial organic carbon
Heterotrophic transformation
Marginal sea
Two Events with Spectacular Moving Structures in a Failed Solar Filament Eruption
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Ou, Yudi
;
Su, Yingna
;
Zhang, Qingmin
;
Ji, Haisheng
;
Li, Leping
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/07/21
Integrated strategy by combining preparative HSCCC with HPLC-UV-QDa for efficient isolation of specific friedelane-type triterpenoids from Salix tetrasperma
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1753, 页码: 13
作者:
Wu, Pei-Qian
;
Fang, Chu-Hong
;
Zhou, Bin
;
Yue, Jian-Min
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/07/25
Salix tetrasperma
Friedelane-type triterpenoids
HSCCC
Multiple detectors
Antiproliferative activity
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Recognizing the function of different silane coupling agents on MXene adsorption/barrier behavior in solvent-borne epoxy coatings: Experimental studies, density functional theory, and molecular dynamics simulations (vol 192, 108453, 2024)
期刊论文
OAI收割
PROGRESS IN ORGANIC COATINGS, 2025, 卷号: 204, 页码: 2
作者:
Pourhashem, Sepideh
;
Hadizadeh, Mohammad Hassan
;
Ji, Xiaohong
;
Zhou, Ziyang
;
Duan, Jizhou
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/11