中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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期刊论文 [309]
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Construction of colorimetric/fluorescent dual-signal probes for the detection of
β
-galactosidase in senescent cells
期刊论文
OAI收割
DYES AND PIGMENTS, 2025, 卷号: 242, 页码: 8
作者:
Dong, Lei
;
Sun, Lu-Lu
;
Li, Wen-Jia
;
Xing, Jing
;
Tan, Mingchao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
beta-Galactosidase
Fluorescence sensing
Cell senescence
Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
;
Chen, Guo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15
作者:
Wang, Yang
;
Fan, Wenhui
;
Guo, Yihao
;
Sun, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/08/20
IPF
EMT
Key kinases
Inhibitors
The Intermediate-mass Black Hole Reverberation Mapping Project: First Detection of Mid-infrared Lags in Prototypical Intermediate-mass Black Holes in NGC 4395 and POX 52
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 989, 期号: 2
作者:
Sun, Jingbo
;
Guo, Hengxiao
;
Zuo, Wenwen
;
Lira, Paulina
;
Gu, Minfeng
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/08/25
Native Ligand-Inspired peptides for c-MET targeted PET probes development
期刊论文
OAI收割
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2025, 页码: 18
作者:
Luo, Renli
;
Tan, Boyu
;
Zhang, Ying
;
Hu, Jing
;
Lin, Jia
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
C-MET
Native ligand
HGF
PET/CT imaging
Radiopharmaceuticals
Peptide probes
Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18
作者:
Yang, Ruirui
;
Wang, Bei
;
Su, Zhaoming
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Detection of an Orphan X-Ray Flare from a Blazar Candidate EP240709a with the Einstein Probe
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 984, 期号: 1
作者:
Liu, Mingjun
;
Zhang, Yijia
;
Wang, Yun
;
Xue, Rui
;
Buckley, David
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/05/05
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors