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Chinese Academy of Sciences Institutional Repositories Grid
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Revolutionizing fixed-dose combinations with long-acting microsphere
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2025, 卷号: 207, 页码: 12
作者:
Hu, Zhenhua
;
Xiao, Xiao
;
Zhang, Guiyun
;
Li, Yuanyuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Fixed-dose combinations
Microsphere
Chronic disease
Long-acting
A holistic strategy for the in-depth discrimination and authentication of 16 citrus herbs and associated commercial products based on machine learning techniques and non-targeted metabolomics
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2025, 卷号: 1745, 页码: 12
作者:
Huang, Yu-shi
;
An, Ya-ling
;
Zheng, Yue-yuan
;
Zhao, Wen-jie
;
Song, Chun-qian
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
Citrus herbs
Discrimination
LC-MS
Machine learning
Differential markers
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13
作者:
Wu, Feifei
;
Li, Huiyu
;
Li, Weiqiang
;
Zhang, Laishun
;
An, Qi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/04/01
Optimization
Hematopoietic progenitor kinase 1
Inhibitor
Cancer immunotherapy
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
In-situ trichosanthin-IL2/pectin dynamic hydrogel activates dendritic cells and reverses T cell exhaustion for post-operative cancer therapy
期刊论文
OAI收割
CHEMICAL ENGINEERING JOURNAL, 2025, 卷号: 505, 页码: 12
作者:
Gu, Zeyun
;
Chen, Guihua
;
Gao, Nan
;
Yao, Shuo
;
Zhang, Xiaoru
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/01
Trichosanthin
IL2
Hydrogel
Postoperative administration
Cancer immunotherapy
Dendritic cells
Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 24
作者:
Cheng, Yifei
;
Chen, Xiaofang
;
Feng, Li
;
Yang, Zhicheng
;
Xiao, Liyun
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/01
A novel pectin-like polysaccharide from Crocus sativus targets Galectin-3 to inhibit hepatic stellate cells activation and liver fibrosis
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 348, 页码: 16
作者:
Tang, Bixi
;
Jin, Can
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/12/11
Liver fibrosis
Galectin 3
Pectin
Polysaccharide structure
Hepatic stellate cell