中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [118]
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Enhanced Bioactivity of Natural Products by Halogenation: A Database Survey and Quantum Chemistry Calculation Study
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10486-10496
作者:
Cao, Ruini
;
Li, Jintian
;
Liao, Qingyi
;
Shao, Mei
;
Zhang, Qian
  |  
收藏
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浏览/下载:7/0
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提交时间:2025/07/25
Discovery of novel antimyeloma agents targeting TRIP13 by molecular modeling and bioassay
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2025, 页码: 14
作者:
Bunu, Samuel Jacob
;
Cai, Haiyan
;
Zhou, Zhaoyin
;
Zhang, Yanlei
;
Lai, Yue
  |  
收藏
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浏览/下载:15/0
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提交时间:2025/06/23
Anterior anchor placement in deltoid ligament augmentation for the treatment of ankle fracture with both syndesmosis and deltoid ligament injury: A biomechanical study
期刊论文
OAI收割
JOURNAL OF ORTHOPAEDIC SURGERY, 2025, 卷号: 33, 期号: 2, 页码: 7
作者:
Fei, Han
;
Li, Yu
;
Li, Ting
;
Li, Changrun
;
Fu, Gang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/18
biomechanics
deltoid ligament
syndesmosis
trauma
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:
Hu, Liuyan
;
Zhao, Zhi
;
Zhang, Shujing
;
Yang, Lei
;
Cui, Wenjie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/06/23
COVID-19
SARS-CoV-2
3CL protease
Peptidomimetic inhibitors
Tetrahydropyrrole spirodihydroindolone
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy
期刊论文
OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:
Li, Cuifeng
;
Wei, Shuqi
;
Sun, Donglin
;
Yang, Zhuo
;
Wang, Qi
  |  
收藏
  |  
浏览/下载:10/0
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提交时间:2025/05/27
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
;
He, Xiao
;
Chen, Gang
  |  
收藏
  |  
浏览/下载:37/0
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提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2025, 页码: 13
作者:
Chen, Jinxiu
;
Shi, Dongmei
;
Jiang, Zhiyang
;
Zou, Renxuan
;
Zhang, Jingyu
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收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/04/01
O. furnacalis
Chitinase
5-alkenylthiazolidinone
1,4-benzodioxane
Dual-chitinases inhibitor
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
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收藏
  |  
浏览/下载:29/0
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提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome
B(MIDA)-directed site-selective intermolecular halofluoroalkylation of alkenes: synthesis of diversely functionalized building blocks
期刊论文
OAI收割
CHEMICAL SCIENCE, 2025, 页码: 8
作者:
Wu, Hengbo
;
Luo, Ruitong
;
Peng, Jingjing
;
Han, Zijian
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收藏
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浏览/下载:31/0
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提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives