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浏览/检索结果: 共686条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17 作者:  Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi   |  收藏  |  浏览/下载：4/0  |  提交时间：2025/08/20 Menin  High binding affinity  Anti-proliferation activity  AML   Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12 作者:  Wu, Feifei;  Sun, Jiaqi;  Xu, Mingyang;  Li, Huiyu;  Wei, Jiarui   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/08/20 Macrocycle  Kinase  Inhibitors  HPK1  Cancer immunotherapy   Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8 作者:  Chen, Yating;  Liu, Qiupei;  Meng, Xianghui;  Cao, Wenxu;  Duo, Lihui   |  收藏  |  浏览/下载：7/0  |  提交时间：2025/08/20 SOS1 inhibitor  KRAS mutation  SOS1-KRAS interaction  Resistance   Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10 作者:  Zhang, Chun;  Yan, Xue;  Gao, Li-Xin;  Cao, Zi-Tong;  Cao, Qing   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/08/20 Imidazo[2,1-b][1,3,4]thiadiazole  Inhibitory activities  Fluorescence imaging  Zebrafish  SHP2   Concise synthesis of NDP-activated uronic acid by an oxidation reaction insertion strategy 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 8, 页码: 7 作者:  Yang, Nana;  Yuan, Rui;  Fu, Xinyue;  Tian, Xiao;  Yu, Jin   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 NDP-uronic acids  Biocatalysis  Enzyme-mediated biomimetic synthesis  Oxidation reaction insertion strategy   Integrative Proteomics and Histone PTMomics Study on Anti-TNBC Effect of JIB-04 期刊论文  OAI收割 JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2025, 页码: 12 作者:  Tao, Shengna;  Guo, Jingli;  Zhang, Jingdan   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/08/20 Proteomics  histone PTMomics  epigenetic inhibitor  JIB-04  TNBC   Covalent sortase A inhibitor, α, β-unsaturated aldehydes, prevents Staphylococcus aureus infection 期刊论文  OAI收割 MICROBIAL PATHOGENESIS, 2025, 卷号: 204, 页码: 12 作者:  Wang, Jianchao;  He, Yuan;  Chu, Chenliang;  Wu, Ziqi;  Zhang, Ting   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/06/23 Sortase A  Covalent inhibitor  alpha  beta-unsaturated aldehydes  Anti-virulence therapy  Staphylococcus aureus   Linaggrenoids A-I, structurally diverse lindenane sesquiterpenoids with anti-hepatic fibrosis effects from Lindera aggregata 期刊论文  OAI收割 PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 10 作者:  Li, Wen-Xian;  Gan, Lu;  Liao, Yi-Ling;  Wu, Yu-Wei;  Zhang, Bai-Hui   |  收藏  |  浏览/下载：12/0  |  提交时间：2025/05/27 Lindera aggregata  Lauraceae  Lindenane sesquiterpenoid  Anti-hepatic fibrosis activity   Green synthesis of 2-trifluoromethylquinoline skeletons via organocatalytic N-[(α-trifluoromethyl)vinyl]isatins CN bond activation 期刊论文  OAI收割 CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 7, 页码: 10 作者:  Ji, Cong-Bin;  Xie, Ding-Xiong;  Chen, Mei;  Lan, Ye-Ying;  Zhang, Bao-Hua   |  收藏  |  浏览/下载：17/0  |  提交时间：2025/07/25 N-[(alpha-Trifluoromethyl)vinyl]isatins  Pfitzinger-type reaction  C-N bond cleavage  2-CF3-quinoline-4-carboxamide  2-CF3-quinoline-4-carboxylicester   Diterpenoids and diarylheptanoids from the fruits of Alpinia zerumbet and their anti-inflammatory activity 期刊论文  OAI收割 FITOTERAPIA, 2025, 卷号: 184, 页码: 10 作者:  Zhang, Zhenghan;  Li, Guangqian;  Luo, Xin;  Xiao, Fang;  Zhang, Yan   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Alpinia zerumbet  Labdane-type diterpenoid  Diarylheptanoid  Anti-inflammatory  ISG pathway  TDDFT ECD calculation