中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [22]
国家天文台 [4]
高能物理研究所 [3]
古脊椎动物与古人类研... [3]
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OAI收割 [46]
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期刊论文 [45]
会议论文 [1]
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2024 [3]
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2020 [1]
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Instrument... [2]
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Design, Synthesis, and Biological Evaluation of Novel Tetrahydroacridin Hybrids with Sulfur-Inserted Linkers as Potential Multitarget Agents for Alzheimer's Disease
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 8, 页码: 17
作者:
Wu, Xiuyuan
;
Ze, Xiaotong
;
Qin, Shuai
;
Zhang, Beiyu
;
Li, Xinnan
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/06/27
Alzheimer's disease
tacrine
cystamine
MTDLs
inhibitors
molecular modeling
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
Discovery of hematopoietic progenitor kinase 1 inhibitors using machine learning-based screening and free energy perturbation
期刊论文
OAI收割
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2024, 页码: 13
作者:
Feng, Dazhi
;
Liu, Bo
;
Chen, Zhiwei
;
Xu, Jinyi
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2024/02/27
HPK1 inhibitor
machine learning
virtual screening
free energy perturbation
structural modification
Pd(II) Complexes of Chiral Proline-Derived Ligands: Application for Dynamic Thermodynamic Resolution of α-Amino Acids and Their Antibacterial Activities
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 88, 期号: 6, 页码: 3808-3821
作者:
Zhu, Huajian
;
Wang, Jiang
;
Lu, Yunfu
;
Soloshonok, Vadim A.
;
Lan, Lefu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/03/27
Cu(II) Complexes with Proline-Derived Schiff Base Ligand: Chemical Resolution of N,C-Unprotected ?-Amino Acids and Their Antibacterial Activity
期刊论文
OAI收割
JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 87, 期号: 19, 页码: 12900-12908
作者:
Zhu, Huajian
;
Wang, Jiang
;
Lu, Yunfu
;
Soloshonok, Vadim A.
;
Lan, Lefu
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/21
Active and Smart Terahertz Electro-Optic Modulator Based on VO2 Structure
期刊论文
OAI收割
ACS APPLIED MATERIALS & INTERFACES, 2022, 卷号: 14
作者:
Ren, Zhuang
;
Xu, Jinyi
;
Liu, Jinming
;
Li, Bolin
;
Zhou, Chun
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/12/23
electro-optic modulation
THz modulation
antireflection
VO2 thin film
smart control
Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:
Liu, Yulin
;
Uras, Giuseppe
;
Onuwaje, Itse
;
Li, Wenlong
;
Yao, Hong
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2022/08/16
Alzheimer's disease
Donepezil
Sulfone group
AChE inhibitor
Inhibiting A 0 aggregation
Neuroprotection
A new genus of pliopithecoid from the late Early Miocene of China and its implications for understanding the paleozoogeography of the Pliopithecoidea
期刊论文
OAI收割
JOURNAL OF HUMAN EVOLUTION, 2020, 卷号: 145, 期号: 1, 页码: 20
作者:
Harrison, Terry
;
Zhang, Yingqi
;
Wei, Guangbiao
;
Sun, Chengkai
;
Wang, Yuan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/09/15
Pliopithecid
Crouzeliid
Dental morphology
Phylogeny
Zoogeography
The Third Data Release of the Beijing?Arizona Sky Survey
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2019, 卷号: 245, 期号: 1, 页码: 4
作者:
Zou, Hu
;
Zhou, Xu
;
Fan, Xiaohui
;
Zhang, Tianmeng
;
Zhou, Zhimin
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/03/12
Sky surveys
Astronomy data reduction
Observational astronomy
Catalogs
The Third Data Release of the Beijing–Arizona Sky Survey
期刊论文
OAI收割
The Astrophysical Journal Supplement Series, 2019, 卷号: 245, 期号: 1, 页码: 4
作者:
Zou,Hu
;
Zhou,Xu
;
Fan,Xiaohui
;
Zhang,Tianmeng
;
Zhou,Zhimin
  |  
收藏
  |  
浏览/下载:240/0
  |  
提交时间:2019/12/02
Sky surveys
Astronomy data reduction
Observational astronomy
Catalogs