中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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Construction of colorimetric/fluorescent dual-signal probes for the detection of
β
-galactosidase in senescent cells
期刊论文
OAI收割
DYES AND PIGMENTS, 2025, 卷号: 242, 页码: 8
作者:
Dong, Lei
;
Sun, Lu-Lu
;
Li, Wen-Jia
;
Xing, Jing
;
Tan, Mingchao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
beta-Galactosidase
Fluorescence sensing
Cell senescence
Design, synthesis and structure-activity relationship studies of novel macrocyclic 2,4-diaminopyrimidines as HPK1 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 12
作者:
Wu, Feifei
;
Sun, Jiaqi
;
Xu, Mingyang
;
Li, Huiyu
;
Wei, Jiarui
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
Macrocycle
Kinase
Inhibitors
HPK1
Cancer immunotherapy
Structural optimization of phthalazine derivatives for anti-HBV activities to improve oral bioavailability
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 10
作者:
Yang, Yurong
;
Xiao, Fuling
;
Zuo, Jianping
;
Yang, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
HBV
Capsid assembly modulators
Structural optimization
Oxidative metabolism
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:
Tian, Lina
;
Xiao, Jian
;
Zeng, Yanping
;
Li, Yangsha
;
Wei, Aihuan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
CDK9
EZH2
Dual target inhibitor
DLBCL
Human gut
Bifidobacterium longum
subsp.
suillum
is enriched in vitro by a pectic polysaccharide isolated from the flowers of
Lilium lancifolium
期刊论文
OAI收割
CARBOHYDRATE POLYMERS, 2025, 卷号: 364, 页码: 14
作者:
Li, Meixia
;
Liu, Renjie
;
Wang, Tao
;
Duo, Lana
;
Chen, Guo
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Polysaccharides
Lilium lancifolium
Human gut microbiota
Bifidobacterium longum subsp. suillum
Discovery of potent anti-idiopathic pulmonary fibrosis (IPF) agents based on an o-aminopyridinyl alkynyl scaffold
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 15
作者:
Wang, Yang
;
Fan, Wenhui
;
Guo, Yihao
;
Sun, Li
;
Hu, Youhong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/08/20
IPF
EMT
Key kinases
Inhibitors
Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Li, Yan-Rong
;
Shangguan, Jinyi
;
Wang, Jian-Min
;
Davies, Ric
;
Santos, Daryl J. D.
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/21
Grain size effect and structural heterogeneity in the shock-induced plastic deformation mechanism of nanocrystalline high-entropy alloys
期刊论文
OAI收割
EUROPEAN JOURNAL OF MECHANICS A-SOLIDS, 2025, 卷号: 112, 页码: 22
作者:
Meng, Yuquan
;
Song, Weidong
;
Liu, Shanshan
;
Wang YJ(王云江)
;
Li, Wanghui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/06/23
Nanocrystalline HEAs
Grain size effect
Shock response
Spallation
Molecular dynamics
Linaggrenoids A-I, structurally diverse lindenane sesquiterpenoids with anti-hepatic fibrosis effects from
Lindera aggregata
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 235, 页码: 10
作者:
Li, Wen-Xian
;
Gan, Lu
;
Liao, Yi-Ling
;
Wu, Yu-Wei
;
Zhang, Bai-Hui
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/05/27
Lindera aggregata
Lauraceae
Lindenane sesquiterpenoid
Anti-hepatic fibrosis activity
UBE4B modulates BET inhibitor sensitivity via KLHL22-JAK2-PIM1 axis in hepatocellular carcinoma
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 19
作者:
Wang, Li
;
Huan, Xia-Juan
;
Song, Shan-Shan
;
Bao, Xu-Bin
;
Tian, Chang-Qing
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/06/23
UBE4B
BET inhibitors
Resistance
KLHL22
JAK2