中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [47]
地球化学研究所 [21]
合肥物质科学研究院 [7]
地理科学与资源研究所 [6]
水生生物研究所 [6]
上海生物化学与细胞生... [6]
更多
采集方式
OAI收割 [119]
内容类型
期刊论文 [116]
会议论文 [2]
学位论文 [1]
发表日期
2025 [9]
2024 [19]
2023 [9]
2022 [14]
2021 [6]
2020 [3]
更多
学科主题
Biochemist... [4]
Environmen... [3]
环境地球化学 [3]
Chemistry [2]
Science & ... [2]
Biochemist... [1]
更多
筛选
浏览/检索结果:
共119条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
ROS-responsive micelles co-loaded dexamethasone and pristimerin to restore the homeostasis of the inflammatory microenvironment for rheumatoid arthritis therapy
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 6, 页码: 6
作者:
Liang, Ruifeng
;
Tu, Yanbei
;
Hua, Peng
;
Huang, Yongzhuo
;
Chen, Meiwan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/05/27
Rheumatoid arthritis
Micelles
Macrophages
Fibroblast-like synoviocytes
Osteoclastogenesis
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Utilization of natural products in diverse pathogeneses of diseases associated with single or double DNA strand damage repair
期刊论文
OAI收割
CHINESE MEDICINE, 2025, 卷号: 20, 期号: 1, 页码: 21
作者:
Liang, Jiali
;
Liu, Wanqing
;
Zhang, Tong
;
Guo, Dean
;
Gong, Jiyu
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
Single or double strands DNA damage
Enzymes in DNA repair
Natural products
Pathogeneses
Clinical treatment strategy of DNA damage involved maladies
Undescribed Phyllocladane-Type Diterpenoids from
Callicarpa giraldii
Hesse ex Rehd. and Their Anti-Neuroinflammatory Activity
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 7, 页码: 27
作者:
Liang, Xu
;
Gong, Qi
;
Xu, Yuting
;
Mu, Jiaxing
;
Tang, Chunping
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/05/27
Callicarpa giraldii
phyllocladane-type diterpenoids
anti-neuroinflammatory activity
calligirlins A-R
Time-Dependent Regulation of Sleep-Wakefulness and Electroencephalographic Characteristics by Spontaneous Running in Male Mice
期刊论文
OAI收割
JOURNAL OF SLEEP RESEARCH, 2025, 页码: 16
作者:
Zhou, Wufang
;
Zhou, Jialin
;
Lu, Qianyu
;
Wang, Long
;
Liang, Yutao
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/05/27
delta power
spontaneous running
theta wave
voluntary exercise
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8
作者:
Cheng, Jie
;
Qian, Hongjie
;
Wang, Yu
;
Liang, Liyu
;
Xu, Wenjing
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/04/01
alcohol
healthy subjects
hemodynamics
PDE5 inhibitor
pharmacokinetics
TPN171
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics of BGT-002, a Novel ATP-Citrate Lyase Inhibitor, in Healthy Chinese Subjects
期刊论文
OAI收割
DRUG DESIGN DEVELOPMENT AND THERAPY, 2025, 卷号: 19, 页码: 1783-1794
作者:
Liu, Yun
;
Yu, Chengyin
;
Zhang, Yifan
;
Xie, Zhifu
;
Wang, Yating
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/04/24
safety
tolerability
pharmacokinetics
pharmacodynamics
BGT-002
novel ACLY inhibitor
YTHDF1 loss in dendritic cells potentiates radiation- induced antitumor immunity via STING-dependent I IFN
期刊论文
OAI收割
JOURNAL OF CLINICAL INVESTIGATION, 2024, 卷号: 134, 期号: 23, 页码: 14
作者:
Wen, Chuangyu
;
Wang, Liangliang
;
Piffko, Andras
;
Chen, Dapeng
;
Yu, Xianbin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/04/01