中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [51]
地球化学研究所 [21]
合肥物质科学研究院 [7]
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OAI收割 [123]
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期刊论文 [120]
会议论文 [2]
学位论文 [1]
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2025 [13]
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Rapid Discovery of Celastrol Derivatives as Potent and Selective PRDX1 Inhibitors via Microplate-Based Parallel Compound Library and In Situ Screening
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13609-13627
作者:
Chen, Shuang
;
Wang, Zhenyu
;
Gao, Jia
;
Wang, Yanlin
;
Liang, Jiayin
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 15
作者:
Xu, Yali
;
Hu, Hao
;
Ran, Yu
;
Zhao, Wensi
;
Guo, An-Di
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Chemoproteomics
Molecular glue degraders
Photo-crosslinking
Protein-protein interactions
Targeted protein degradation
Ultrabright ratiometric Raman-guided epilepsy surgery by intraoperatively visualizing proinflammatory microglia
期刊论文
OAI收割
CELL REPORTS MEDICINE, 2025, 卷号: 6, 期号: 6, 页码: 28
作者:
Wang, Cong
;
Li, Zhi
;
Zhu, Xiao
;
Sun, Wanbing
;
Ding, Yue
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
ROS-responsive micelles co-loaded dexamethasone and pristimerin to restore the homeostasis of the inflammatory microenvironment for rheumatoid arthritis therapy
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 6, 页码: 6
作者:
Liang, Ruifeng
;
Tu, Yanbei
;
Hua, Peng
;
Huang, Yongzhuo
;
Chen, Meiwan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/05/27
Rheumatoid arthritis
Micelles
Macrophages
Fibroblast-like synoviocytes
Osteoclastogenesis
Neuroprotection and Enhanced Learning and Memory Abilities of Steamed American Ginseng (
Panax quinquefolium
L.) Based on Zebrafish
期刊论文
OAI收割
FOOD SCIENCE & NUTRITION, 2025, 卷号: 13, 期号: 6, 页码: 17
作者:
Yang, Yuting
;
Liang, Shuyun
;
Xu, Mengdan
;
Liu, Xiaokang
;
Guo, Yunlong
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
learning and memory
neuroprotection
Panax quinquefolius
L.
steaming
total saponins
zebrafish
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Utilization of natural products in diverse pathogeneses of diseases associated with single or double DNA strand damage repair
期刊论文
OAI收割
CHINESE MEDICINE, 2025, 卷号: 20, 期号: 1, 页码: 21
作者:
Liang, Jiali
;
Liu, Wanqing
;
Zhang, Tong
;
Guo, Dean
;
Gong, Jiyu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/05/27
Single or double strands DNA damage
Enzymes in DNA repair
Natural products
Pathogeneses
Clinical treatment strategy of DNA damage involved maladies
Undescribed Phyllocladane-Type Diterpenoids from
Callicarpa giraldii
Hesse ex Rehd. and Their Anti-Neuroinflammatory Activity
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 7, 页码: 27
作者:
Liang, Xu
;
Gong, Qi
;
Xu, Yuting
;
Mu, Jiaxing
;
Tang, Chunping
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/05/27
Callicarpa giraldii
phyllocladane-type diterpenoids
anti-neuroinflammatory activity
calligirlins A-R
Time-Dependent Regulation of Sleep-Wakefulness and Electroencephalographic Characteristics by Spontaneous Running in Male Mice
期刊论文
OAI收割
JOURNAL OF SLEEP RESEARCH, 2025, 页码: 16
作者:
Zhou, Wufang
;
Zhou, Jialin
;
Lu, Qianyu
;
Wang, Long
;
Liang, Yutao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/05/27
delta power
spontaneous running
theta wave
voluntary exercise
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery