中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [77]
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OAI收割 [193]
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期刊论文 [190]
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Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Peng, Chang
;
Jiang, Haowen
;
Jing, Liya
;
Yang, Wenhua
;
Guan, Xiaotong
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Discovery of novel biaryl urea derivatives against IL-1/3 release with low toxicity based on NEK7 inhibitor
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 12
作者:
Wang, Leibo
;
Zhu, Kehan
;
Tian, Ziyang
;
Wang, Haoyu
;
Jia, Yulei
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/01/14
NLRP3 inflammasome
NEK7
NLRP3-NEK7
Inhibitors
Harnessing acylhydrazone-oxime exchange reaction to achieve diverse synthesis of glycosite-specific antibody-drug conjugates
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 9
作者:
Xia, Fei
;
Liu, Zhi
;
Hang, Jiaying
;
Xu, Hao
;
Xiao, Yuting
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:
Tang, Mingze
;
Zhou, Xuan
;
Shen, Qianqian
;
Fang, Chen
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/22
Receptor -interacting protein kinase 1
Histone deacetylases
Inhibitor
Molecular dynamics (MD) simulation
ADMET analysis
Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20
作者:
Luo, Menglan
;
Ye, Yunfei
;
Tang, Lu
;
Kan, Weijuan
;
Chen, Lin
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/26
Menin
Covalent inhibitor
Antitumor
Degradation
Germacrane-type sesquiterpenes from Artemisia atrovirens and their anti-inflammatory activity
期刊论文
OAI收割
FITOTERAPIA, 2024, 卷号: 179, 页码: 11
作者:
Tang, Chunping
;
Zheng, Yongzhe
;
Shao, Zhengguang
;
Ke, Chang-Qiang
;
Feng, Zheling
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/26
Artemisia atrovirens
Atrovirenolides C -I
Atrovirenoic acid G
Diatrovirenolides A -B
DFT NMR calculation
TDDFT ECD calculation
The ALMA-QUARKS Survey: Fibers' Role in Star Formation Unveiled in an Intermediate-mass Protocluster Region of the Vela D Cloud
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2024, 卷号: 976, 期号: 2
作者:
Yang, Dongting
;
Liu, Hong-Li
;
Liu, Tie
;
Tej, Anandmayee
;
Liu, Xunchuan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/01/06
miCGR: interpretable deep neural network for predicting both site-level and gene-level functional targets of microRNA
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 26, 期号: 1, 页码: 13
作者:
Wu, Xiaolong
;
Zhang, Lehan
;
Tong, Xiaochu
;
Wang, Yitian
;
Zhang, Zimei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/25
MicroRNA
target prediction
chaos game representation
deep learning
convolutional neural network
The ALMA-QUARKS Survey: Fibers' Role in Star Formation Unveiled in an Intermediate-mass Protocluster Region of the Vela D Cloud
期刊论文
OAI收割
The Astrophysical Journal, 2024, 卷号: 976, 期号: 2
作者:
Yang,Dongting
;
Liu,Hong-Li
;
Liu,Tie
;
Tej,Anandmayee
;
Liu,Xunchuan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/23
DNA-Encoded Noncanonical Substrate Library for Protease Profiling
期刊论文
OAI收割
CHEMBIOCHEM, 2024, 页码: 12
作者:
Zhang, Huiya
;
Xing, Yuyu
;
Yang, Yixuan
;
Tang, Bixi
;
Zong, Zhaoyun
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2024/12/16
Protease substrate
DNA-encoded library
Combinatorial peptide library
High-throughput screening
Covalent inhibitor
Noncanonical peptide