中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共193条,第1-10条 帮助

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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:  
Guma, Samuel Desta;  Song, Kang;  Sun, Haiguo;  Yang, Lei;  Zhou, Zhaoyin
  |  收藏  |  浏览/下载:2/0  |  提交时间:2025/08/20
Design and synthesis of CDK9/EZH2 dual-target inhibitors to achieve synergistic antitumor effects 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 14
作者:  
Tian, Lina;  Xiao, Jian;  Zeng, Yanping;  Li, Yangsha;  Wei, Aihuan
  |  收藏  |  浏览/下载:3/0  |  提交时间:2025/08/20
The Intermediate-mass Black Hole Reverberation Mapping Project: First Detection of Mid-infrared Lags in Prototypical Intermediate-mass Black Holes in NGC 4395 and POX 52 期刊论文  OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 989, 期号: 2
作者:  
Sun, Jingbo;  Guo, Hengxiao;  Zuo, Wenwen;  Lira, Paulina;  Gu, Minfeng
  |  收藏  |  浏览/下载:10/0  |  提交时间:2025/08/25
Methotrexate exerts antitumor immune activity and improves the clinical efficacy of immunotherapy in patients with solid tumors 期刊论文  OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2025, 卷号: 17, 期号: 801, 页码: 18
作者:  
Yang, Ruirui;  Wang, Bei;  Su, Zhaoming;  Song, Ying;  Zhang, Yingying
  |  收藏  |  浏览/下载:6/0  |  提交时间:2025/08/20
An Asymmetric Reductive Amination Synthesis of Ritlecitinib Using (S)-α-Methylbenzylamine as Chiral Auxiliary 期刊论文  OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2025, 页码: 10
作者:  
Dong, Hongkun;  Bonku, Emmanuel Mintah;  Zhang, Yuxuan
  |  收藏  |  浏览/下载:21/0  |  提交时间:2025/07/25
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19
作者:  
Yin, Wen;  Xu, Heng;  Bai, Zhonghao;  Wu, Yue;  Zhang, Yan
  |  收藏  |  浏览/下载:31/0  |  提交时间:2025/04/01
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:  
Guma, Samuel Desta;  Zhou, Zhaoyin;  Song, Kang;  Yang, Feipu;  Suo, Jin
  |  收藏  |  浏览/下载:22/0  |  提交时间:2024/12/11
Synthesis and evaluation of hybrid molecules as RIPK1 and HDACs dual inhibitors 期刊论文  OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2024, 卷号: 1318, 页码: 13
作者:  
Tang, Mingze;  Zhou, Xuan;  Shen, Qianqian;  Fang, Chen;  Peng, Xia
  |  收藏  |  浏览/下载:29/0  |  提交时间:2024/08/22
Direct Reductive N-alkylation of Amines with Carboxylic Esters 期刊论文  OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 7
作者:  
Zhang, Yuxuan;  Bonku, Emmanuel Mintah;  Yang, Xingbang;  Zhu, Fuqiang;  Jiang, Xiangrui
  |  收藏  |  浏览/下载:22/0  |  提交时间:2025/01/14
Iron-Catalyzed Cross-Coupling Reactions of Alkyl Grignard Reagents with Alkenyl Carbonate 期刊论文  OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2024, 页码: 8
作者:  
Qin, Hongjian;  Yang, Xingbang;  Mintah Bonku, Emmanuel;  Zhu, Fuqiang;  Abduahadi, Safomuddin
  |  收藏  |  浏览/下载:20/0  |  提交时间:2024/12/11