中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
武汉物理与数学研究所 [4]
地理科学与资源研究所 [2]
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寒区旱区环境与工程研... [1]
南京地理与湖泊研究所 [1]
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iSwitch采集 [2]
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期刊论文 [22]
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2023 [3]
2022 [1]
2021 [3]
2019 [7]
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2016 [1]
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A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 14
作者:
Wang, Yunxia
;
Pan, Ziqi
;
Mou, Minjie
;
Xia, Weiqi
;
Zhang, Hongning
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/08
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6
作者:
Xu, Lei
;
Xuyan, Xuyang
;
Minmi, Minmin
;
Wang, Zhiji
;
Shee, Chao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2023/10/17
Activator
PTPs
Inhibitor
Thieno[2
b ]quinoline derivatives
Diffuse large B-cell lymphoma
RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 11
作者:
Wang, Yunxia
;
Chen, Zhen
;
Pan, Ziqi
;
Huang, Shijie
;
Liu, Jin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/10/17
Learning with uncertainty to accelerate the discovery of histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitors
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2022, 页码: 14
作者:
Wang, Dong
;
Wu, Zhenxing
;
Shen, Chao
;
Bao, Lingjie
;
Luo, Hao
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/04/10
uncertainty estimation
graph neural network
KDM1A
LSD1 inhibitors
upper confidence bound method
virtual screening
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:
Fu, Weitao
;
Zhang, Minkui
;
Liao, Jianing
;
Tang, Qing
;
Lei, Yixuan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/03/21
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 13
作者:
Zhang, Huibing
;
Chen, Li-Nan
;
Yang, Dehua
;
Mao, Chunyou
;
Shen, Qingya
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/11/04
Development of MIF/IL-1β biosensors for discovery of critical quality attributes and potential allergic rhinitis targets from clinical real-world data by intelligent algorithm coupled with in vitro an
期刊论文
OAI收割
BIOSENSORS & BIOELECTRONICS, 2021, 卷号: 194, 页码: 113608
作者:
Ma, Lijuan
;
Zheng, Yanfei
;
Wang, Ji
;
Li, Qianqian
;
Zeng, Jingqi
;
Wang, Zijian
;
Hou, Tingjun
;
Zhang, Yang
;
Li, Mingshuang
;
Shen, Rongmin
;
Chen, Xuemei
;
Qin, Jingbo
;
Lei, Leting
;
Xia, Qing
;
Wang, Qi
;
Qiao, Yanjiang
;
Wu, Zhisheng
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/03/23
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays
期刊论文
OAI收割
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:
Hou, Tingjun
;
Li, Dan
;
Chang, Shan
;
Xu, Lei
;
Sun, Huiyong
  |  
收藏
  |  
浏览/下载:275/0
  |  
提交时间:2019/06/24
Androgen receptor
AR ligand
Virtual screening
AR agonist
AR antagonist
Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects
期刊论文
OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1665-1701
作者:
Chen, Fahu
;
Fu, Bojie
;
Xia, Jun
;
Wu, Duo
;
Wu, Shaohong
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2020/06/03
Physical geography in China
Living environment
Climate change
Tibetan Plateau
Human-environment interactions
Major advances in studies of the physical geography and living environment of China during the past 70 years and future prospects
期刊论文
OAI收割
SCIENCE CHINA-EARTH SCIENCES, 2019, 卷号: 62, 期号: 11, 页码: 1665-1701
作者:
Chen, Fahu
;
Fu, Bojie
;
Xia, Jun
;
Wu, Duo
;
Wu, Shaohong
  |  
收藏
  |  
浏览/下载:113/0
  |  
提交时间:2020/05/19
Physical geography in China
Living environment
Climate change
Tibetan Plateau
Human-environment interactions