中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [49]
新疆理化技术研究所 [4]
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OAI收割 [64]
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期刊论文 [64]
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2026 [2]
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Investigation of a clinical trial drug VV261 as a potent antiviral candidate against Chikungunya virus
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2026, 卷号: 11, 期号: 1, 页码: 3
作者:
Zhang, Yumin
;
Tang, Sheng
;
Chen, Lu
;
Song, Shufen
;
Cao, Junyuan
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2026/04/01
Soluble epoxide hydrolase deficiency rescues heart failure with preserved ejection fraction by targeting cytochrome P450 2E1
期刊论文
OAI收割
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2026, 卷号: 210, 页码: 98-108
作者:
Zhang, Min
;
Chen, Chen
;
Liu, Xinxing
;
Zhou, Zhou
;
Li, Gen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2026/01/28
Soluble epoxide hydrolase
Desuccinylation
Epoxyeicosatrienoic acids
Heart failure with preserved ejection fraction
The oral nucleoside drug VV116 is a promising candidate for treating Nipah virus infection
期刊论文
OAI收割
EMERGING MICROBES & INFECTIONS, 2025, 卷号: 14, 期号: 1, 页码: 4
作者:
Zhang, Yumin
;
Yao, Yanfeng
;
Song, Shufen
;
Gao, Ge
;
Peng, Yun
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2026/01/28
VV116
Nipah virus
oral nucleoside drug
antiviral effect
hamster model
Uncovering key anti-inflammatory constituents and mechanism of Wuwei Xiaodu Decoction by a combined strategy of phytochemistry, AIDD, network pharmacology, and in vitro and in vivo assay
期刊论文
OAI收割
BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2025, 卷号: 25, 期号: 1, 页码: 20
作者:
Li, Binghui
;
Zhou, Zhaoyin
;
Zhang, Yong
;
Zhu, Jing
;
Liu, Qiyuan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/12/04
Wuwei xiaodu decoction
Active components
Anti-inflammation effect
RAW264.7 cells
Mouse model
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Identification of Cannabigerol-Derived Dual CB
2
Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357
作者:
Yang, Wenjiao
;
Sun, Haiguo
;
Ji, Jing
;
Chen, Hai
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/08/20
F-CPI: A Multimodal Deep Learning Approach for Predicting Compound Bioactivity Changes Induced by Fluorine Substitution
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 13
作者:
Zhang, Qian
;
Yin, Wenhai
;
Chen, Xinyao
;
Zhou, Aimin
;
Zhang, Guixu
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2025/02/28
Discovery of the potent covalent inhibitor with an acrylate warhead for SARS-CoV-2 3CL protease
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 112, 页码: 5
作者:
Shen, Wen
;
Chen, Xinyao
;
Zhou, Liping
;
Cheng, Yan
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2024/10/21
COVID-19
SARS-CoV-2 3CL pro inhibitor
Drug design
Antiviral activities
Identification of Dihydrobenzofuran Neolignans as Novel PDE4 Inhibitors and Evaluation of Antiatopic Dermatitis Efficacy in DNCB-Induced Mice Model
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4855-4869
作者:
Gu, Chenming
;
Liu, Jiayuan
;
Qian, Fei
;
Yu, Wenchao
;
Huang, Doudou
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/05/07
Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8
作者:
Shu, Guangzhao
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2024/06/27
Cannabidiol
Stress-induced hyperthermia
Phencyclidine-induced negative symptoms of
schizophrenia model
5-HT 1A receptor