机构

• 上海药物研究所 [56]
• 中国科学院大学 [1]

采集方式

• OAI收割 [56]
• iSwitch采集 [1]

内容类型

• 期刊论文 [57]

发表日期

• 2025 [11]
• 2024 [16]
• 2023 [7]
• 2022 [7]
• 2021 [4]
• 2019 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共57条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Pharmacokinetics, mass balance, and metabolism of [14C]PLB1004, a selective and irreversible EGFR-TKI in humans 期刊论文  OAI收割 CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 14 作者:  Liu, Donghui;  Li, Qian;  Yan, Shu;  Zhang, Xinyue;  Li, Weiqiang   |  收藏  |  浏览/下载：38/0  |  提交时间：2025/04/01 PLB1004  [C-14]PLB1004  Radioactivity  Mass balance  EGFR-TKI   Pharmacokinetics, mass balance, and metabolism of [14C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans 期刊论文  OAI收割 CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12 作者:  Gao, Lei;  Ma, Sheng;  Yan, Shu;  Zhang, Hua;  Tian, Ling   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/07/25 FCN-437c  CDK4/6 inhibitor  Mass balance  Radiopharmacokinetics  Drug metabolism   Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug-Drug Interaction Predictions 期刊论文  OAI收割 CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY, 2025, 卷号: 14, 期号: 7, 页码: 1273-1284 作者:  Wu, Yali;  Loer, Helena Leonie Hanae;  Zhang, Yifan;  Zhong, Dafang;  Jiang, Yong   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/08/20 Characterization of the specific proteins to which HH-A, a drug that alleviates ischemic brain injury, binds in rat plasma 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 7, 页码: 15 作者:  Zhao, Jie;  Zheng, Yuandong;  Lei, Peng;  Zhang, Yuying   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Stroke  Covalent binding  HH-A  Ischemic brain injury  Proteomics   Characterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modeling 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2025, 卷号: 15, 期号: 5, 页码: 15 作者:  He, Yifei;  Zhu, Chenggu;  Lei, Peng;  Yang, Chen;  Zhang, Yifan   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 PROTAC  Vepdegestrant (ARV-471)  Radiolabeling  In vitro-in vivo extrapolation (IVIVE)  Physiologically based pharmacokinetic  (PBPK) model   Quantification of serum daratumumab in multiple myeloma patients by LC-MS/MS, comparison with ELISA 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2025, 卷号: 255, 页码: 7 作者:  Li, Weiqiang;  Tian, Zhuoran;  Yu, Xiong;  Xu, Hongyu;  Huang, Fang   |  收藏  |  浏览/下载：37/0  |  提交时间：2025/02/28 Multiple myeloma  Daratumumab  LC-MS/MS  Surrogate peptide   Design, Synthesis, and biological evaluation of 7H-Pyrrolo[2,3-d] pyrimidines as potent HPK1 kinase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 119, 页码: 13 作者:  Wu, Feifei;  Li, Huiyu;  Li, Weiqiang;  Zhang, Laishun;  An, Qi   |  收藏  |  浏览/下载：20/0  |  提交时间：2025/04/01 Optimization  Hematopoietic progenitor kinase 1  Inhibitor  Cancer immunotherapy   Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307 作者:  Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie   |  收藏  |  浏览/下载：34/0  |  提交时间：2025/04/01 In vitro and In vivo Drug Metabolism Analysis of BPI-460372-A Covalent TEAD1/3/4 Inhibitor 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2025, 页码: 15 作者:  Liu, Xiaoyun;  Zhong, Dafang;  Tang, Chongzhuang;  Xu, Xiaofeng;  Lan, Hong   |  收藏  |  浏览/下载：13/0  |  提交时间：2025/04/24 Hippo signaling pathway  TEAD inhibitor  covalent inhibitor  BPI-460372  UHPLC-Orbitrap-HRMS  cysteine  S-conjugate beta-lyase.   PEGylation of Dipeptide Linker Improves Therapeutic Index and Pharmacokinetics of Antibody-Drug Conjugates 期刊论文  OAI收割 BIOCONJUGATE CHEMISTRY, 2025, 页码: 11 作者:  Long, Jing;  Shao, Ting;  Wang, Yongmei;  Chen, Tianzhi;  Chen, Yuning   |  收藏  |  浏览/下载：35/0  |  提交时间：2025/04/01