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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [18]
武汉物理与数学研究所 [8]
近代物理研究所 [7]
深圳先进技术研究院 [4]
长春应用化学研究所 [4]
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期刊论文 [74]
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2026 [1]
2025 [4]
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2022 [5]
2021 [13]
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Cell Biolo... [2]
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Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 23
作者:
Zheng, Jiefang
;
Tian, Yaxin
;
Cheng, Jiaxin
;
Hu, Zhengtao
;
Zhang, Junchi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/12/04
Antidepressants
Multimodal monoaminergic compounds
Triple monoamine reuptake inhibitors
5-HT 3A R antagonist
Aryl-spirocyclic diamine derivatives
The anti-aging potential of VA'S new derivatives through metabolomic profiling
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2025, 卷号: 15, 期号: 1, 页码: 14
作者:
Tan, Li
;
Wu, Jiang
;
Wang, Jiewen
;
Zhang, Hongkang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2026/01/28
MVA
Metabolomics
Anti-aging
Molecular synthesis
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Discovery of multi-chitinase inhibitors cinnamyl thiazolidinone compounds as candidates for insect growth regulators via ligand-based optimization strategies
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 306, 页码: 14
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Fu, Haoyu
;
Li, Yan
;
Zou, Renxuan
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2025/05/27
Multi-chitinase inhibitor
Cinnamaldehyde compounds
Thiazolidinone compounds
Ligand-based optimization
Insect growth regulators (IGRs)
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
Atomic-scale compositional complexity ductilizes eutectic phase towards creep-resistant Al-Ce alloys with improved fracture toughness
期刊论文
OAI收割
ACTA MATERIALIA, 2024, 卷号: 276, 页码: 120133
作者:
Yi, Meng
;
Zhang, Peng
;
Deng, Sihao
;
Xue, Hang
;
Yang, Chong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2026/03/18
A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 2, 页码: 215
作者:
Zhang Bibo
;
Li Bo
;
Xie Yongsheng
;
Chang Shuaikang
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2023/07/18
DCZ0358
apoptosis
cell cycle arrest
multiple myeloma
JAK2/STAT3 pathway
Rational Design and Identification of Novel Piperine Derivatives as Multichitinase Inhibitors
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2022, 卷号: 70, 期号: 33, 页码: 10326-10336
作者:
Jiang, Zhiyang
;
Shi, Dongmei
;
Li, Huilin
;
He, Danchan
;
Zhu, Kai
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2022/09/30
Asian corn borer
chitinase
piperine derivate
multichitinase inhibitor
insect growth regulator (IGR)
Chemo- and Site-Selective Lysine Modification of Peptides and Proteins under Native Conditions Using the Water-Soluble Zolinium
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 14
作者:
Sun, Haiguo
;
Xi, Mengyu
;
Jin, Qiang
;
Zhu, Zhengdan
;
Zhang, Yani
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2022/09/30