中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
近代物理研究所 [19]
金属研究所 [16]
上海药物研究所 [16]
心理研究所 [10]
广州地球化学研究所 [6]
昆明植物研究所 [5]
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OAI收割 [111]
内容类型
期刊论文 [111]
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2024 [7]
2023 [12]
2022 [11]
2021 [17]
2020 [10]
2019 [7]
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Pharmacolo... [2]
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Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/09/10
Anti-inflammatory germacrane-type sesquiterpene lactones from Vernonia sylvatica
期刊论文
OAI收割
CHINESE JOURNAL OF NATURAL MEDICINES, 2024, 卷号: 22, 期号: 6, 页码: 568-576
作者:
Wang, Min
;
Li, Han
;
Hu, Bintao
;
Tang, Chunping
;
Xu, Hui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/09/26
Vernonia sylvatica
Germacrane-type sesquiterpene lactone
Sylvaticalides A-H
Anti-inflammatory
NF-kappa B path- way
ISG pathway
Dihydrocelastrol induces cell death and suppresses angiogenesis through BCR/AP-1/junb signalling in diffuse large B cell lymphoma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2024, 卷号: 754, 页码: 11
作者:
Lai, Yue
;
Guo, Shushan
;
Tang, Qiongwei
;
Chang, Gaomei
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/07
Dihydrocelastrol
Angiogenesis
Apoptosis
Jun B
p65
Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma
期刊论文
OAI收割
HAEMATOLOGICA, 2024, 卷号: 109, 期号: 4, 页码: 1206-1219
作者:
Chen, Gege
;
Gao, Xuejie
;
Jia, Xinyan
;
Wang, Yingcong
;
Xu, Li
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/05/07
A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK