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Design and synthesis of novel site-specific antibody-drug conjugates that target TROP2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 110, 页码: 16
作者:
Luo, Caili
;
Ren, Anni
;
Jin, Zixuan
;
Zhang, Jianxin
;
Shi, Wei
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/22
TROP2
Antibody-drug conjugate (ADC)
Site-specific
Glycoengineering
Affinity-directed conjugation
Cooperative management can mitigate trade-offs between livestock production and ecological functions to promote grassland sustainability
期刊论文
OAI收割
AGRICULTURE ECOSYSTEMS & ENVIRONMENT, 2024, 卷号: 370
作者:
Li, Shanshan
;
Jiao, Jianxin
;
Degen, Allan
;
Wang, Wenyin
;
Qi, Tianyun
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/27
Hiding Payload Inside the IgG Fc Cavity Significantly Enhances the Therapeutic Index of Antibody-Drug Conjugates
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Shi, Wei
;
Zhang, Jianxin
;
Liu, Liya
;
Li, Wanzhen
;
Liu, Zhi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
Nanoplateletsomes restrain metastatic tumor formation through decoy and active targeting in a preclinical mouse model
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 8, 页码: 3427-3447
作者:
Zhang, Longlong
;
Zhu, Yuefei
;
Wei, Xunbin
;
Chen, Xing
;
Li, Yang
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/09/30
Nanoplateletsome
Breast cancer
Tumor metastasis
Circulating tumor cells
Nanodecoy
Immunosuppressive micrometastatic environment
Lung pre-metastasis
A Traceless Site-Specific Conjugation on Native Antibodies Enables Efficient One-Step Payload Assembly
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 11
作者:
Zeng, Yue
;
Shi, Wei
;
Dong, Qian
;
Li, Wanzhen
;
Zhang, Jianxin
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2022/08/30
Acyl Transfer
Anti-Tumor
One-Step Synthesis
Site-Specific ADCs
Thioester
One-step synthesis of site-specific antibody-drug conjugates by reprograming IgG glycoengineering with LacNAc-based substrates
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2417-2428
作者:
Shi, Wei
;
Li, Wanzhen
;
Zhang, Jianxin
;
Li, Tiehai
;
Song, Yakai
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/08/16
Site-specific ADCs
ENGase
LacNAc
One-step assembly
Potent in vivo efficacy
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
期刊论文
OAI收割
NATURE, 2022, 卷号: 604, 期号: 7906, 页码: 502-+
作者:
Trubetskoy, Vassily
;
Pardinas, Antonio F.
;
Qi, Ting
;
Panagiotaropoulou, Georgia
;
Awasthi, Swapnil
  |  
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2022/05/16
Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 期号: D1, 页码: D27-D38
作者:
Xue, Yongbiao
;
Bao, Yiming
;
Zhang Zhang
;
Zhao, Wenming
;
Xiao, Jingfa
  |  
收藏
  |  
浏览/下载:119/0
  |  
提交时间:2022/04/02
Database Resources of the National Genomics Data Center,China National Center for Bioinformation in 2022
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 页码: 27-38
作者:
Xue Yongbiao
;
Bao Yiming
;
Zhang Zhang
;
Zhao Wenming
;
Xiao Jingfa
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2023/04/17
Database Resources of the National Genomics Data Center,China National Center for Bioinformation in 2021
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2022, 卷号: 50, 页码: 27-38
作者:
Xue Yongbiao
;
Bao Yiming
;
Zhang Zhang
;
Zhao Wenming
;
Xiao Jingfa
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2023/04/17