中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
Torque work of origin-destination flows: Quantifying urban place centrality from a physical perspective
期刊论文
OAI收割
COMPUTERS ENVIRONMENT AND URBAN SYSTEMS, 2025, 卷号: 121, 页码: 102311
作者:
Yan, Xiaorui
;
Pei, Tao
;
Song, Ci
;
Fang, Zidong
;
Liu, Xiaohan
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/07/18
Place centrality
Origin-destination flows
Torque work
Multiscale analysis
Intra-day dynamic
Urban science
Qingfeiyin decoction in idiopathic pulmonary fibrosis: Lung-targeted components and PI3K-AKT modulation
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 351, 页码: 14
作者:
Liu, Yongqi
;
Song, Luyao
;
Chen, Shiyi
;
Li, Jiajia
;
Peng, Xionghua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Idiopathic pulmonary fibrosis
Qingfeiyin
Baicalin
Oroxylin a
Network pharmacology
Molecular docking
Molecular dynamic simulation
Multistage reaction characteristics and kinetic effects of temperature on pyrite oxidation in black rock layers:Insights from high-speed railway subgrade filling materials
期刊论文
OAI收割
CASE STUDIES IN CONSTRUCTION MATERIALS, 2025, 卷号: 22, 页码: 16
作者:
Liu, Zihang
;
Huang, Kang
;
Dai, Zhangjun
;
Yu, Fei
;
Song, Xiaodong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/27
Black rock layers
Temperature
High-speed rail
SO42-concentration
Subgrade
Pyrite
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Competition between shrubs and grasses in a shrub-encroached temperate grassland: Implications from nitrogen acquisition
期刊论文
OAI收割
BIOLOGY AND FERTILITY OF SOILS, 2025, 卷号: N/A
作者:
Li, Zhaoxi
;
Tian, Yuqiang
;
Song, Minghua
;
Yu, Mengmeng
;
Li, Xiaobing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/07/18
Competition
N-15 labelling
Nitrogen uptake
Shrubs
Slope locations
Soil microbial regulation
Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 12, 页码: 12862-12880
作者:
Guo, Jing
;
Tang, Haotian
;
Zhao, Wenchao
;
Li, Yong
;
Song, Shukai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Detection of two TeV gamma-ray outbursts from NGC 1275 by LHAASO
期刊论文
OAI收割
Monthly Notices of the Royal Astronomical Society, 2025, 卷号: 540, 期号: 2, 页码: 1860-1869
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/06/23
methods: data analysis
methods: statistical
galaxies: active
galaxies: jets
gamma
rays: general
A born ultramassive white dwarf-hot subdwarf super-Chandrasekhar candidate
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 6
作者:
Luo, Changqing
;
Li J(李蛟)
;
Zheng, Chuanjie
;
Liu DD(刘栋栋)
;
Li ZW(李振威)
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/05/05
stars:horizontal branch
subdwarfs
binaries:close
white dwarfs
stars:neutron
supernovae:general
Strategic Amino Acid Mutations in CPD Cleavage Motif: Impacts on Hydrolysis and C-Terminal Modification Efficiency
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2025, 卷号: 41, 期号: 3, 页码: 592-600
作者:
Yashinov, Ansor
;
Zou, Xiangman
;
Hang, Jiayin
;
Liu, Zhi
;
Song, Fengnan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/06/23
Protein engineering
C-Terminal modification
Cysteine protease domain
Self-cleavage tag
AlphaFold2