中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
海洋研究所 [4]
高能物理研究所 [3]
上海药物研究所 [2]
化学研究所 [1]
采集方式
OAI收割 [7]
iSwitch采集 [3]
内容类型
期刊论文 [10]
发表日期
2024 [1]
2019 [2]
2018 [3]
2016 [3]
2011 [1]
学科主题
Marine & F... [1]
Oceanograp... [1]
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Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 17, 页码: 15220-15245
作者:
Saidahmatov, Abdusaid
;
Li, Jianan
;
Xu, Shihao
;
Hu, Xiaobei
;
Gao, Xiangqian
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/10/21
Design, synthesis and biological evaluation of bromophenol-thiazolylhydrazone hybrids inhibiting the interaction of translation initiation factors eIF4E/eIF4G as multifunctional agents for cancer treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 153-170
作者:
Wang, Lijun
;
Guo, Chuanlong
;
Li, Xiuxue
;
Yu, Xuemin
;
Li, Xiangqian
  |  
收藏
  |  
浏览/下载:193/0
  |  
提交时间:2019/08/29
Bromophenol-thiazolylhydrazone hybrids
Synthesis
Multifunctional agents
eIF4E/eIF4G interaction
Autophagy
ROS
Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2 ',3,3 '-Tetrabromo-4,4 ',5,5 '-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice
期刊论文
OAI收割
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 5, 页码: 1839-1850
作者:
Li, Chao
;
Luo, Jiao
;
Guo, Shuju
;
Jia, Xiaoling
;
Guo, Chuanlong
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2019/08/28
type 2 diabetes mellitus
protein tyrosine phosphatase 1B
insulin resistance
hypoglycemic activity
dyslipidemia
Ph-triggered peptide self-assembly for targeting imaging and therapy toward angiogenesis with enhanced signals
期刊论文
iSwitch采集
Acs applied materials & interfaces, 2018, 卷号: 10, 期号: 9, 页码: 7871-7881
作者:
Qian, Yixia
;
Wang, Weizhi
;
Wang, Zihua
;
Jia, Xiangqian
;
Han, Qiuju
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/04/23
Ph-triggered
Vegfr2
Self-assembly
Biaimaging
Cancer therapy
Biochemical Studies and Molecular Dynamic Simulations Reveal the Molecular Basis of Conformational Changes in DNA Methyltransferase-1
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2018, 卷号: 13, 期号: 3, 页码: 772-781
作者:
Ye, Fei
;
Kong, Xiangqian
;
Zhang, Hao
;
Liu, Yan
;
Shao, Zhiyuan
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Selectivity, cell permeability and oral availability studies of novel bromophenol derivative HPN as protein tyrosine phosphatase 1B inhibitor
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2018, 卷号: 175, 期号: 1, 页码: 140-153
作者:
Luo, Jiao
;
Xu, Qi
;
Jiang, Bo
;
Zhang, Renshuai
;
Jia, Xiaoling
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/08/20
Switchable Liposomes: Targeting-Peptide-Functionalized and pH-Triggered Cytoplasmic Delivery
期刊论文
OAI收割
ACS Applied Materials & Interfaces, 2016, 卷号: 8, 期号: 29, 页码: 18658-18663
作者:
Han, Quju
;
Wang, Weizhi
;
Jia, Xiangqian
;
Qian, Yixia
;
Li, Qian
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2016/12/29
switchable liposomes
pH-responsive peptide
VEGFR2
drug delivery
cancer therapy
Micromixer based preparation of functionalized liposomes and targeting drug delivery
期刊论文
iSwitch采集
Acs medicinal chemistry letters, 2016, 卷号: 7, 期号: 4, 页码: 429-434
作者:
Jia, Xiangqian
;
Wang, Weizhi
;
Han, Qiuju
;
Wang, Zihua
;
Jia, Yunhong
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/04/23
Nanocarrier
Her2
Antitumor
Ylffvfer
Her2 targeting peptides screening and applications in tumor imaging and drug delivery
期刊论文
iSwitch采集
Theranostics, 2016, 卷号: 6, 期号: 8, 页码: 1261-1273
作者:
Geng, Lingling
;
Wang, Zihua
;
Jia, Xiangqian
;
Han, Qiuju
;
Xiang, Zhichu
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/04/23
Her2 targeting peptide
Tumor imaging
Drug delivery
Breast cancer
Md simulation
Cloning and nucleotide sequence of D-hydantoinase gene of marine polyphosphate-accumulating bacterium, Halomonas sp YSR-3
期刊论文
OAI收割
CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2011, 卷号: 29, 期号: 5, 页码: 917-921
作者:
Ren Shiying
;
Li Xiangqian
;
Jia Jianbo
;
Liu Fei
;
Xiao Tian
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2012/07/03
Halomonas Sp Ysr-3
D-hydantoinase
Polyphosphate-accumulating Bacterium