中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [24]
国家天文台 [1]
高能物理研究所 [1]
中国科学院大学 [1]
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OAI收割 [26]
iSwitch采集 [1]
内容类型
期刊论文 [27]
发表日期
2025 [3]
2024 [2]
2023 [4]
2022 [5]
2021 [2]
2020 [3]
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学科主题
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浏览/检索结果:
共27条,第1-10条
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Unveiling p65 as the target of diphyllin in ameliorating metabolic dysfunction-associated steatotic liver disease via targeted protein degradation technology
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2025, 卷号: 16, 页码: 12
作者:
Zhu, Xuejing
;
Zhang, Lei
;
Cui, Wenqian
;
Wang, Liangjie
;
Xu, Fengjing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/07/25
metabolic dysfunction-associated steatotic liver disease
diphyllin
p65
targeted protein degradation technology
NRF2
Macrophage SUCLA2 coupled glutaminolysis manipulates obesity through AMPK
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Peng, Chang
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2025/04/01
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
Rh(II)-Catalyzed Selective C(sp
3
)-H/C(sp
2
)-H Bonds Cascade Insertion to Construct [6-8-6] Benzo-Fused Scaffold
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 50, 页码: 10719-10728
作者:
Yu, Tao
;
Fang, Feifei
;
Shou, Haowen
;
Li, Yazhou
;
Qu, Zhiyan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/01/14
Unraveling the complex roles of macrophages in obese adipose tissue: an overview
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2024, 页码: 32
作者:
Peng, Chang
;
Chen, Jun
;
Wu, Rui
;
Jiang, Haowen
;
Li, Jia
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/02/19
obesity
inflammation
adipose tissue macrophages
adipose tissue homeostasis
Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15
期刊论文
OAI收割
JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14
作者:
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2023/10/17
Glucuronyl C5-epimerase
Growth differentiation factor-15
Obesity
Energy expenditure
Ubiquitination
The development and benefits of metformin in various diseases
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 44
作者:
Dong, Ying
;
Qi, Yingbei
;
Jiang, Haowen
;
Mi, Tian
;
Zhang, Yunkai
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2023/10/17
metformin
metabolism
cancer
aging
neurological disorder
Integrative multi-omics and drug-response characterization of patient-derived prostate cancer primary cells
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 6, 页码: 3013-3028
作者:
Wang, Ziruoyu
;
Li, Yanan
;
Zhao, Wensi
;
Jiang, Shuai
;
Huang, Yuqi
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/03/27
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 13
作者:
Xu, Yanhong
;
Ye, Xiaotong
;
Zhou, Yang
;
Cao, Xinyu
;
Peng, Shiqiao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/04/10
sodium butyrate
succinylation
HMGCS2
ketogenesis
SIRT5
Dithiocarbazate-copper complex loaded thermosensitive hydrogel for lung cancer therapy via tumor in situ sustained-release
期刊论文
OAI收割
INORGANIC CHEMISTRY FRONTIERS, 2022, 页码: 12
作者:
Deng, JunGang
;
Peng, Chang
;
Hou, LiXia
;
Wu, YouRu
;
Liu, Wei
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2022/11/11