机构

• 上海药物研究所 [24]
• 宁波材料技术与工程研... [5]
• 化学研究所 [4]
• 心理研究所 [3]
• 动物研究所 [2]
• 合肥物质科学研究院 [2]
• 更多

采集方式

• OAI收割 [47]

内容类型

• 期刊论文 [47]

发表日期

• 2025 [1]
• 2024 [3]
• 2023 [6]
• 2022 [6]
• 2021 [9]
• 2020 [3]
• 更多

学科主题

• Chemistry [1]
• Instrument... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共47条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885 作者:  Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/07/25 Synergism of salvianolic acid B and ginsenoside Rg1 magnifies the therapeutic potency against ischemic stroke 期刊论文  OAI收割 NEUROREPORT, 2024, 卷号: 35, 期号: 16, 页码: 1041-1051 作者:  Shen, Haishang;  Zhang, Yuhan;  Shao, Yanan;  Chen, Siqi;  Yin, Ping   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/11/26 Bliss independence statistical model  ginsenoside Rg1  glycerophospholipid metabolism  ischemic stroke  salvianolic acid B  synergistic effect   Endoplasmic reticulum-targeted delivery of celastrol and PD-L1 siRNA for reinforcing immunogenic cell death and potentiating cancer immunotherapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 8, 页码: 3643-3660 作者:  Wang, Jie;  Zhang, Zilong;  Zhuo, Yan;  Zhang, Zhuan;  Chen, Rongrong   |  收藏  |  浏览/下载：48/0  |  提交时间：2024/09/26 Chemoimmunotherapy  Targeted drug delivery  Endoplasmic reticulum  Endoplasmic reticulum stress  Immunogenic cell death  siRNA  Exosomes  Colorectal cancer   Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial 期刊论文  OAI收割 NATURE MEDICINE, 2024 作者:  Qin, Jianjun;  Xue, Liyan;  Hao, Anlin;  Guo, Xiaofeng;  Jiang, Tao   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/11/22 Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：45/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   Hepatic glucuronyl C5-epimerase combats obesity by stabilising GDF15 期刊论文  OAI收割 JOURNAL OF HEPATOLOGY, 2023, 卷号: 79, 期号: 3, 页码: 14 作者:  He, Fei;  Jiang, Haowen;  Peng, Chang;  Wang, Tingting;  Xiao, Rongrong   |  收藏  |  浏览/下载：81/0  |  提交时间：2023/10/17 Glucuronyl C5-epimerase  Growth differentiation factor-15  Obesity  Energy expenditure  Ubiquitination   Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21 作者:  Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui   |  收藏  |  浏览/下载：69/0  |  提交时间：2023/10/17 Multi-source underwater DOA estimation using PSO-BP neural network based on high-order cumulant optimization 期刊论文  OAI收割 CHINA COMMUNICATIONS, 2023, 页码: 18 作者:  Chen, Haihua;  Zhang, Jingyao;  Jiang, Bin;  Cui, Xuerong;  Zhou, Rongrong   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/12/04 Direction-of-arrival estimation  Estimation  Neural networks  Mathematical models  Training  Covariance matrices  Biological neural networks  particle swarm optimization (PSO) algorithm  PSO-BP neural network  gaussian colored noise  multiple sources  higher-order cumulant   Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214 作者:  Zhou, Zehui;  Zhou, Guizhen;  Zhou, Chuan;  Fan, Zisheng;  Cui, Rongrong   |  收藏  |  浏览/下载：40/0  |  提交时间：2024/03/27 Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347 作者:  Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/27