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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Green synthesis of 2-trifluoromethylquinoline skeletons
via
organocatalytic
N
-[(
α
-trifluoromethyl)vinyl]isatins CN bond activation
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 7, 页码: 10
作者:
Ji, Cong-Bin
;
Xie, Ding-Xiong
;
Chen, Mei
;
Lan, Ye-Ying
;
Zhang, Bao-Hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
N-[(alpha-Trifluoromethyl)vinyl]isatins
Pfitzinger-type reaction
C-N bond cleavage
2-CF3-quinoline-4-carboxamide
2-CF3-quinoline-4-carboxylicester
Chat-microreactor: A large-language-model-based assistant for designing continuous flow systems
期刊论文
OAI收割
CHEMICAL ENGINEERING SCIENCE, 2025, 卷号: 311
作者:
Pan, Yongqi
;
Xiao, Qinfan
;
Zhao, Fangyu
;
Li ZH(李振豪)
;
Liu, Jianyang
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2025/04/21
Flow chemistry
Microreactor
Large language models
Machine learning
Multi-phase dispersion
Discovery of novel Bis-amide analogue ST12 for the treatment of inflammatory bowel diseases (IBD) by inhibiting NLRP3 inflammasome activation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 159, 页码: 14
作者:
Sun, Zhiqiang
;
Zang, Qinru
;
Xu, Chenglong
;
Zhang, Xuewen
;
Kang, Zhenghui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2025/05/27
Anti-inflammatory agents
Nitric oxide (NO)
NLRP3 inflammasome
Inflammatory bowel diseases (IBD)
Species difference in the excretion routes of Ciprofol (HSK3486) in rats and humans: Contribution of hepatic transporters and renal UDP-glucuronosyltransferase enzymes
期刊论文
OAI收割
DRUG METABOLISM AND DISPOSITION, 2025, 卷号: 53, 期号: 6, 页码: 10
作者:
Zhou, Yufan
;
Guo, Zitao
;
Meng, Jian
;
Kang, Xinyao
;
Zhang, Menglin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Excretion
Glucuronide metabolites
Multidrug resistance protein
Species differences
UGT enzymes
ATR-FTIR Coupled With Machine Learning Provides a Fast Method for Identifying and Distinguishing 55 Varieties of Fruit-Derived Medicinal Materials
期刊论文
OAI收割
PHYTOCHEMICAL ANALYSIS, 2025, 页码: 13
作者:
Zhao, Wen-jie
;
An, Ya-ling
;
Song, Chun-qian
;
Huang, Yu-shi
;
Zhang, Li-jie
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
ATR-FTIR
fruit-derived medicinal materials
machine learning
species discrimination
Mechanical behavior and failure characteristics of limestone-concrete specimens with different prefabricated fracture angles under compressive-shear loading
期刊论文
OAI收割
CONSTRUCTION AND BUILDING MATERIALS, 2025, 卷号: 476, 页码: 12
作者:
Huang, Kang
;
Huang, Shuling
;
Ding, Xiuli
;
Zhang, Yuting
;
Liu, Zihang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/06/27
Compression-shear loading
Limestone-concrete interface
Cracking behavior
Failure characteristics
Digital Image Correlation (DIC)
In-orbit characterization of radio-frequency ion micropropulsion in Taiji-1
期刊论文
OAI收割
PHYSICAL REVIEW D, 2025, 卷号: 111, 期号: 10, 页码: 10
作者:
Ma, Longfei
;
He, Jianwu
;
Yang, Chao
;
Zhang, Chu
;
Duan, Li
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/07/22
Effect of Vertical Strain and Hydration Time on Mechanical Behavior and Microstructure of Expansive Soil
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF GEOMECHANICS, 2025, 卷号: 25, 期号: 5, 页码: 14
作者:
Chi, Ze-Cheng
;
Dai, Zhang-Jun
;
Huang, Kang
;
Wang, Wei
;
Chen, Shan-Xiong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/27
Expansive soil
Swelling pressure
Hydration mechanism
Microstructure
Vertical strain