机构

• 上海药物研究所 [306]
• 上海神经科学研究所 [4]
• 广州地球化学研究所 [3]
• 中国科学院大学 [3]
• 新疆理化技术研究所 [2]
• 生物物理研究所 [1]
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采集方式

• OAI收割 [321]
• iSwitch采集 [3]

内容类型

• 期刊论文 [322]
• 会议论文 [2]

发表日期

• 2023 [12]
• 2022 [22]
• 2021 [24]
• 2020 [18]
• 2019 [13]
• 2018 [13]
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学科主题

• Biochemist... [2]
• Agronomy [1]
• Cell Biolo... [1]
• Chemistry [1]
• Infectious... [1]
• Life Scien... [1]
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筛选

浏览/检索结果: 共324条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Computing the relative binding affinity of ligands based on a pairwise binding comparison network 期刊论文  OAI收割 Nature computational science, 2023, 卷号: 3, 期号: 10, 页码: 860-872 作者:  Yu, Jie;  Li, Zhaojun;  Chen, Geng;  Kong, Xiangtai;  Hu, Jie   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/26 Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2023, 页码: 9 作者:  Li, Rui;  Chen, Lin;  He, Xinheng;  Cao, Duanhua;  Zhang, Zehong   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/12/11 Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/25 αExtractor: a system for automatic extraction of chemical information from biomedical literature 期刊论文  OAI收割 SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 4 作者:  Xiong, Jiacheng;  Liu, Xiaohong;  Li, Zhaojun;  Xiao, Hongzhong;  Wang, Guangchao   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/12/08 STING agonist-boosted mRNA immunization via intelligent design of nanovaccines for enhancing cancer immunotherapy 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2023, 卷号: 10, 期号: 10, 页码: 16 作者:  Zhou, Lei;  Yi, Wenzhe;  Zhang, Zehong;  Shan, Xiaoting;  Zhao, Zitong   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 vaccine  mRNA  STING  cancer immunotherapy  nanoparticles   Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 24 作者:  Li, Xiao;  Li, Fei;  Ye, Fei;  Guo, Haotian;  Chen, Wentao   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 Synthesis, cytotoxicity, and pharmacokinetic evaluations of niclosamide analogs for anti-SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 11 作者:  Li, Rui;  Zhang, Zherui;  Huang, Shuhong;  Peng, Ke;  Jiang, Hualiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 SARS-CoV-2  Niclosamide analogs  Cytotoxicity  Pharmacokinetic  SKP2 inhibition   Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11 作者:  Xu, Haiyu;  Li, Shufen;  Liu, Jiayuan;  Cheng, Jinlong;  Kang, Liping   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 COVID-19  traditional Chinese medicine  TCMT-NDRD  antivirus  anti-inflammation   MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules 期刊论文  OAI收割 JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42 作者:  Liu, Xiaohong;  Zhang, Wei;  Tong, Xiaochu;  Zhong, Feisheng;  Li, Zhaojun   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 De novo molecule design  Generative models  Deep learning  Virtual screening  Compound quality control   Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3327-3347 作者:  Shan, Bin;  Hou, Hui;  Zhang, Keke;  Li, Rui;  Shen, Chang   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27