中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
化学研究所 [10]
西安光学精密机械研究... [9]
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期刊论文 [94]
会议论文 [1]
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2024 [4]
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浏览/检索结果:
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KinomeMETA: a web platform for kinome-wide polypharmacology profiling with meta-learning
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2024, 页码: 9
作者:
Li, Zhaojun
;
Qu, Ning
;
Zhou, Jingyi
;
Sun, Jingjing
;
Ren, Qun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/06/27
Energy preservation for skeletal muscles: Shenqi Fuzheng injection prevents tissue wasting and restores bioenergetic profiles in a mouse model of chemotherapy-induced cachexia
期刊论文
OAI收割
PHYTOMEDICINE, 2024, 卷号: 125, 页码: 13
作者:
Li, Wei
;
Zhang, Zijia
;
Berik, Entezar
;
Liu, Yawen
;
Pei, Wenqiang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/04/09
Shenqi Fuzheng injection
Chemotherapy-induce cachexia
Bioenergetic profiles
Glycolysis
TCA cycle
lipid metabolism
Shenqi Fuzheng injection alleviates chemotherapy-induced cachexia by restoring glucocorticoid signaling in hypothalamus
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 3, 页码: 431-434
作者:
Berik, Entezar
;
Zhang, Zijia
;
Li, Wei
;
Liu, Yawen
;
Chen, Sihan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/06/27
Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634
作者:
Xiong, Jiacheng
;
Cui, Rongrong
;
Li, Zhaojun
;
Zhang, Wei
;
Zhang, Runze
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/05/07
Drug metabolism
Aldehyde oxidase
Transfer learning
Graph neural network
Kinase inhibitor
Computing the relative binding affinity of ligands based on a pairwise binding comparison network
期刊论文
OAI收割
Nature computational science, 2023, 卷号: 3, 期号: 10, 页码: 860-872
作者:
Yu, Jie
;
Li, Zhaojun
;
Chen, Geng
;
Kong, Xiangtai
;
Hu, Jie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/26
αExtractor: a system for automatic extraction of chemical information from biomedical literature
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 4
作者:
Xiong, Jiacheng
;
Liu, Xiaohong
;
Li, Zhaojun
;
Xiao, Hongzhong
;
Wang, Guangchao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/12/08
Automated pattern generation for swarm robots using constrained multi-objective genetic programming
期刊论文
OAI收割
SWARM AND EVOLUTIONARY COMPUTATION, 2023, 卷号: 81
作者:
Fan, Zhun
;
Wang, Zhaojun
;
Li, Wenji
;
Zhu, Xiaomin
;
Hu, Bingliang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/07/17
Gene regulatory network (GRN)
Entrapping pattern generation
Self-organization
Constrained multi-objective genetic
programming (CMOGP)
Learning ensembles of process-based models for high accurately evaluating the one-hundred-year carbon sink potential of China's forest ecosystem
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 6, 页码: e17243
作者:
Wang, Zhaosheng
;
Li, Renqiang
;
Guo, Qingchun
;
Wang, Zhaojun
;
Huang, Mei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/09/07
Learning ensembles of process-based models
Random forest model
Forest ecosystem
Carbon sink potential
MolFilterGAN: a progressively augmented generative adversarial network for triaging AI-designed molecules
期刊论文
OAI收割
JOURNAL OF CHEMINFORMATICS, 2023, 卷号: 15, 期号: 1, 页码: 42
作者:
Liu, Xiaohong
;
Zhang, Wei
;
Tong, Xiaochu
;
Zhong, Feisheng
;
Li, Zhaojun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/27
De novo molecule design
Generative models
Deep learning
Virtual screening
Compound quality control
Multi-omics profiling of PC-3 cells reveals bufadienolides-induced lipid metabolic remodeling by regulating long-chain lipids synthesis and hydrolysis
期刊论文
OAI收割
METABOLOMICS, 2023, 卷号: 19, 期号: 2, 页码: 13
作者:
Zhang, Rong
;
Zhang, Zijia
;
Wu, Wenyong
;
Shi, Jingying
;
Berk, Entezar
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
Bufadienolides
Prostate cancer
Lipidomics
Transcriptomics
ELOVL6
PLD1