机构

• 上海药物研究所 [18]
• 地理科学与资源研究所 [5]
• 金属研究所 [1]
• 宁波材料技术与工程研... [1]
• 地球化学研究所 [1]
• 沈阳自动化研究所 [1]
• 更多

采集方式

• OAI收割 [27]

内容类型

• 期刊论文 [27]

发表日期

• 2025 [1]
• 2024 [4]
• 2023 [4]
• 2022 [1]
• 2021 [2]
• 2020 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共27条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序作者升序作者降序题名升序题名降序发表日期升序发表日期降序 Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24 作者:  Li, Na;  Wang, Linlin;  Hu, Xinyuan;  Xu, Haiyan;  Yang, Bowen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/08/20 Voltage-gated sodium channel 1.8  Conformational restriction  Pharmacokinetic  Structure-activity relationship  Analgesic   Golgi-derived extracellular vesicle production induced by SARS-CoV-2 envelope protein 期刊论文  OAI收割 APOPTOSIS, 2024, 页码: 13 作者:  Li, Qiguang   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/12/25 Extracellular vesicle  SARS-CoV-2  Envelope protein  Ion channel  Golgi fragmentation   Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12912-12931 作者:  He, Guoxue;  Zheng, Yueming;  Chang, Shunzhen;  Wang, Long;  Yang, Xiaohao   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/09/26 Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割 NATURE CHEMICAL BIOLOGY, 2024, 页码: 29 作者:  Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li   |  收藏  |  浏览/下载：58/0  |  提交时间：2024/03/25 An LQT2-related mutation in the voltage-sensing domain is involved in switching the gating polarity of hERG 期刊论文  OAI收割 BMC BIOLOGY, 2024, 卷号: 22, 期号: 1, 页码: 14 作者:  Liu, Zhipei;  Wang, Feng;  Yuan, Hui;  Tian, Fuyun;  Yang, Chuanyan   |  收藏  |  浏览/下载：49/0  |  提交时间：2024/03/13 hERG  K525N  Gating Polarity  Voltage-Sensing Domain  LQT2   Disruption of ER ion homeostasis maintained by an ER anion channel CLCC1 contributes to ALS-like pathologies 期刊论文  OAI收割 CELL RESEARCH, 2023, 卷号: 33, 期号: 7, 页码: 497-515 作者:  Guo, Liang;  Mao, Qionglei;  He, Ji;  Liu, Xiaoling;  Piao, Xuejiao   |  收藏  |  浏览/下载：40/0  |  提交时间：2024/03/27 Remediation of Cd contaminated paddy fields by intercropping of the high- and low- Cd-accumulating rice cultivars 期刊论文  OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 878, 页码: 163133 作者:  Xue, Tao;  Liao, Xiaoyong;  Li, Hongying;  Xie, Yunhe;  Wei, Wei   |  收藏  |  浏览/下载：108/0  |  提交时间：2023/05/06 Remediation  Rice intercropping  Cd-contaminated soil  Phytoremediation  Cd removal   Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model 期刊论文  OAI收割 FEBS JOURNAL, 2023, 页码: 19 作者:  Yang, Chuanyan;  Tian, Fuyun;  Hu, Mei;  Kang, Chunlan;  Ping, Meixuan   |  收藏  |  浏览/下载：84/0  |  提交时间：2023/10/17 glycocalyx  H+ leak  lysosome acidification  proton channel  TMEM175   Slight transition in Chinese atmospheric Pb isotopic fingerprinting due to increasing foreign Pb 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2023, 卷号: 323, 页码: 121296 作者:  Tao, Zhenghua;  Guo, Qingjun;  Liu, Congqiang;  Wei, Rongfei   |  收藏  |  浏览/下载：48/0  |  提交时间：2023/05/06 Lead isotopes  Source appointment  ?208Pb value  Foreign Pb   Loss of MLKL ameliorates liver fibrosis by inhibiting hepatocyte necroptosis and hepatic stellate cell activation 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 11, 页码: 5220-5236 作者:  Guo, Ren;  Jia, Xiaohui;  Ding, Zhenbin;  Wang, Gang;  Jiang, Mengmeng   |  收藏  |  浏览/下载：71/0  |  提交时间：2022/08/30 Mixed lineage kinase domain-like protein  MLKL  liver fibrosis  liver parenchymal cells  hepatocyte  hepatic stellate cells  necroptosis