中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [45]
上海药物研究所 [17]
西北高原生物研究所 [11]
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OAI收割 [114]
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期刊论文 [115]
会议论文 [1]
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Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
Regulation of interstitial fluid flow in adventitia along vasculature by heartbeat and respiration
期刊论文
OAI收割
ISCIENCE, 2024, 卷号: 27, 期号: 4, 页码: 22
作者:
Li, Hongyi
;
Li, Bei
;
Luo, Wenqi
;
Qi, Xi
;
Hao, You
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/12/06
D3Rings: A Fast and Accurate Method for Ring System Identification and Deep Generation of Drug-Like Cyclic Compounds
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2024, 卷号: 64, 期号: 3, 页码: 724-736
作者:
Ma, Minfei
;
Zhang, Xinben
;
Zhou, Liping
;
Han, Zijian
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2024/03/13
D3CARP: a comprehensive platform with multiple-conformation based docking, ligand similarity search and deep learning approaches for target prediction and virtual screening
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2023, 卷号: 164, 页码: 8
作者:
Shi, Yulong
;
Zhang, Xinben
;
Yang, Yanqing
;
Cai, Tingting
;
Peng, Cheng
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/10/17
Target prediction
Virtual screening
Molecular docking
Ligand similarity search
Deep learning
The Stellar Abundances and Galactic Evolution Survey (SAGES). I. General Description and the First Data Release (DR1)
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2023, 卷号: 268, 期号: 1, 页码: 18
作者:
Fan, Zhou
;
Zhao, Gang
;
Wang, Wei
;
Zheng, Jie
;
Zhao, Jingkun
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2023/11/14
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 18, 页码: 11
作者:
Xu, Haiyu
;
Li, Shufen
;
Liu, Jiayuan
;
Cheng, Jinlong
;
Kang, Liping
  |  
收藏
  |  
浏览/下载:99/0
  |  
提交时间:2023/10/17
COVID-19
traditional Chinese medicine
TCMT-NDRD
antivirus
anti-inflammation
Resilient Event-Triggered Model Predictive Control for Adaptive Cruise Control Under Sensor Attacks
期刊论文
OAI收割
IEEE/CAA Journal of Automatica Sinica, 2023, 卷号: 10, 期号: 3, 页码: 807-809
作者:
Zhijian Hu
;
Rong Su
;
Kai Zhang
;
Zeyuan Xu
;
Renjie Ma
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/03/02
Fused-ring alpha-pyrones from intramolecular C-H activation and their lipids-lowering activity associated with LXR-IDOL-LDLR axis regulation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 244, 页码: 11
作者:
Mao, Yingle
;
Li, Jiaomeng
;
Tang, Chunping
;
Ma, Biao
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
C-H activation
One-pot intramolecular cyclization
?-Pyrone derivatives
LDL uptaking
LXR-IDOL-LDLR axis
In vivo lipids-lowering effect
Disruption of C/EBP beta-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2022, 卷号: 20, 期号: 1, 页码: 19
作者:
Wu, Dan
;
Zhang, Yanqiong
;
Zhao, Chunhui
;
Li, Qiuyue
;
Zhang, Junhong
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2023/04/10
C/EBP beta-Clec7a axis
Neuroinflammation
Neuropathic Pain
NLRP3 Inflammasome-mediated Pyroptosis
D3AI-Spike: A deep learning platform for predicting binding affinity between SARS-CoV-2 spike receptor binding domain with multiple amino acid mutations and human angiotensin-converting enzyme 2
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2022, 卷号: 151, 页码: 8
作者:
Han, Jiaxin
;
Liu, Tingting
;
Zhang, Xinben
;
Yang, Yanqing
;
Shi, Yulong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
D3AI-Spike
ELISA
Protein -protein interaction
COVID-19
Deep learning