机构

• 上海药物研究所 [13]
• 植物研究所 [2]
• 兰州化学物理研究所 [2]
• 地质与地球物理研究所 [1]
• 水生生物研究所 [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2025 [1]
• 2024 [3]
• 2023 [3]
• 2022 [4]
• 2021 [2]
• 2020 [1]
• 更多

学科主题

• 材料科学与物理化学 [2]
• Biodiversi... [1]
• Environmen... [1]
• Optics [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Ligand-binding assays validated for quantitative bioanalysis of a novel antibody-drug conjugate in monkey serum and related application in a nonclinical study 期刊论文  OAI收割 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2025, 卷号: 131, 页码: 11 作者:  Hou, Yingying;  Miao, Jie;  Sun, Yajun;  Shi, Lili;  Lu, Ouyang   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/04/01 ADC  LBA  Validation  GLP  PK   Development of an ELISA with acidification treatment for an antibody conjugate incorporating Exatecans 期刊论文  OAI收割 ANALYTICAL BIOCHEMISTRY, 2024, 卷号: 690, 页码: 8 作者:  Zhang, Yingying;  Yun, Xi;  Ouyang, Lu;  Zhang, Xianjing;  Gong, Likum   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/06/27 Antibody-drug conjugate  Camptothecin  Exatecan  Bioanalysis  Pharmacokinetics   Eliminating drug target interference with specific antibody or its F(ab′)2 fragment in the bridging immunogenicity assay 期刊论文  OAI收割 BIOANALYSIS, 2024, 页码: 14 作者:  Deng, Xiaojie;  Hou, Yingying;  Yuan, Wenyi;  Yang, Hongzhou;  Guo, Ruowen   |  收藏  |  浏览/下载：295/0  |  提交时间：2024/04/09 anti-drug antibody  IgE  immunogenicity  mitigation  target interference   Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14 作者:  Tao, Yimin;  Lu, Wei;  Gao, Jinli;  Yang, Shuangshuang;  Ruan, Chaoyi   |  收藏  |  浏览/下载：37/0  |  提交时间：2024/03/13 antibody-drug conjugate (ADC)  bioanalysis  anti-drug antibody (ADA)  ligand binding assay (LBA)  ADA-tolerant assay   Development, methodological evaluation and application of a cell-based TRF assay for analysis of ADCC activity 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 7 作者:  Zhu, Xiao;  Gong, Likun;  Qin, Qiuping   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/10/17 Antibody-dependent cell-mediated cytotoxicity  Time-resolved fluorescence  Monoclonal antibody  Antibody-Drug Conjugate  Eu  NK-92 cells   Development, Validation and Application of a Bridging ELISA for Detection of Antibodies against GQ1001 in Cynomolgus Monkey Serum 期刊论文  OAI收割 MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1684 作者:  Liu, Tingting;  Sun, Yajun;  Deng, Xiaojie;  Shi, Lili;  Chen, Wenyi   |  收藏  |  浏览/下载：16/0  |  提交时间：2024/03/27 antibody-drug conjugate  immunogenicity  anti-drug antibody  bridging ELISA   Development of a bridging ELISA for detection of antibodies against ZV0203 in cynomolgus monkey serum 期刊论文  OAI收割 JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2023, 卷号: 119, 页码: 10 作者:  Liu, Tingting;  Tong, Yongliang;  Gao, Jinli;  Fang, Wenjing;  Wu, Junliang   |  收藏  |  浏览/下载：41/0  |  提交时间：2023/04/10 Antibody-drug conjugate  Immunogenicity  Anti-drug antibody  Bridging ELISA   Current Analytical Strategies for Antibody-Drug Conjugates in Biomatrices 期刊论文  OAI收割 MOLECULES, 2022, 卷号: 27, 期号: 19, 页码: 17 作者:  Qin, Qiuping;  Gong, Likun   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/11/11 ADC  antibody  payload  LBA  LC-MS  bioanalysis  immunogenicity  interference   Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay 期刊论文  OAI收割 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 页码: 11 作者:  Zhou, Liping;  Liu, Tingting;  Mo, Mengxia;  Shi, Yulong;  Wu, Leyun   |  收藏  |  浏览/下载：32/0  |  提交时间：2022/11/11 Enzyme-linked immunosorbent assays for quantification of MMAE-conjugated ADCs and total antibodies in cynomolgus monkey sera 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL ANALYSIS, 2022, 卷号: 12, 期号: 4, 页码: 645-652 作者:  Pei, Min;  Liu, Tingting;  Ouyang, Lu;  Sun, Jianhua;  Deng, Xiaojie   |  收藏  |  浏览/下载：56/0  |  提交时间：2022/11/11 Monomethyl auristatin E  Antibody-drug conjugates  Pharmacokinetics  Trophoblast cell surface antigen 2