机构

• 上海药物研究所 [16]
• 水生生物研究所 [1]

采集方式

• OAI收割 [17]

内容类型

• 期刊论文 [17]

发表日期

• 2022 [1]
• 2019 [1]
• 2018 [1]
• 2017 [1]
• 2016 [1]
• 2015 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共17条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 The discovery of a novel series of potential ERR alpha inverse agonists based on p-nitrobenzenesulfonamide template for triple-negative breast cancer in vivo 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 125-134 作者:  Gao, Zhipei;  Wang, Tianxiao;  Li, Rui;  Du, Yongli;  Lv, Han   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/01/18 ERR alpha  TNBC  p-Nitrobenzenesulfonamide  inverse agonist   Substituent-Oriented Synthesis of Substituted Pyrazoles/Chromeno[3,2-c]pyrazoles via Sequential Reactions of Chromones/3-Chlorochromones and Tosylhydrazones 期刊论文  OAI收割 JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 9, 页码: 5913-5921 作者:  Dai, Tianzi;  Li, Qunyi;  Zhang, Xiaofei;  Yang, Chunhao   |  收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01 Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 144, 页码: 692-700 作者:  Du, Yongli;  Zhang, Yanhui;  Ling, Hao;  Li, Qunyi;  Shen, Jingkang   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitors  N-(2,5-diethoxy-phenyl)-methane sulfonamide  Type 2 diabetes mellitus  PTP1B   Development of Selective Cyclin-Dependent Kinase 4 Inhibitors for Antineoplastic Therapies 期刊论文  OAI收割 ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2017, 卷号: 17, 期号: 5, 页码: 646-657 作者:  Guan, Haixing;  Du, Yongli;  Han, Weiwei;  Shen, Jingkang;  Li, Qunyi   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Anti-cancer agents  cell cycle  clinical trials  cyclin-dependent kinases 4  selective inhibitors  structure activity relationship (SAR)   Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 118, 页码: 27-33 作者:  Liu, Peihong;  Du, Yongli;  Song, Lianhua;  Shen, Jingkang;  Li, Qunyi   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  Methyl salicylate derivatives  ABC type PTP1B inhibitor   Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 21, 页码: 7079-7088 作者:  Liu, Peihong;  Du, Yongli;  Song, Lianhua;  Shen, Jingkang;  Li, Qunyi   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Type 2 diabetes mellitus  PTP1B  Inhibitor  Structure-activity relationships   Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 15, 页码: 4891-4898 作者:  Du, Yongli;  Ling, Hao;  Zhang, Meng;  Shen, Jingkang;  Li, Qunyi   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitor  N-(2,5-Diethoxy-phenyl)-methanesulfonamide  Type 2 diabetes mellitus  Insulin signaling   thehittoleadoptimizationof12344a9ahexahydro1hxanthenesasglucocorticoidreceptorantagonists 期刊论文  OAI收割 chinesechemicalletters, 2014, 卷号: 25, 期号: 5, 页码: 693 作者:  Zhu Yanhui;  Zhang Meng;  Li Qunyi;  Liu Qing;  Zhang Jie   |  收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01 SUBSTITUTED SALICYLALDEHYDES  DERIVATIVES  MICE  Glucocorticoid receptor  Antagonist  1,2,3,4,4a,9a-Hexahydroxanthene  Structure-activity relationship  Lead optimization   Selection and characterization of single-chain recombinant antibodies against spring viraemia of carp virus from mouse phage display library 期刊论文  OAI收割 JOURNAL OF VIROLOGICAL METHODS, 2013, 卷号: 194, 期号: 1-2, 页码: 178-184 作者:  Liu, Hong;  Zheng, Xiaocong;  Zhang, Feng;  Yu, Li;  Zhang, Xiaohua 收藏  |  浏览/下载：58/0  |  提交时间：2014/08/06 Phage display  Single-chain fragment variable  Spring viraemia of carp virus   Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay 期刊论文  OAI收割 ANALYTICAL BIOCHEMISTRY, 2011, 卷号: 418, 期号: 1, 页码: 66-72 作者:  Li, Qunyi;  Rottlander, Mario;  Xu, Mingkai;  Christoffersen, Claus Tornby;  Frederiksen, Kristen   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 KCNQ  Kv7  Patch clamp  Stable cell line  Thallium flux  (86)Rubidium flux  Potassium channel opener  High-throughput screening