中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
中国科学院大学 [8]
上海药物研究所 [2]
烟台海岸带研究所 [2]
生物物理研究所 [1]
上海营养与健康研究所 [1]
采集方式
iSwitch采集 [8]
OAI收割 [6]
内容类型
期刊论文 [14]
发表日期
2025 [1]
2024 [3]
2011 [1]
2010 [4]
2009 [2]
2008 [3]
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学科主题
Pharmacolo... [1]
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浏览/检索结果:
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Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:
Zeng, Gongruixue
;
Xu, Gaoya
;
Gao, Lixin
;
Zheng, Xiaoli
;
Chi, Xinglong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
Proteasome inhibitors
Macrocycle
Stability
Anti-cancer activities
Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10
作者:
Yu, Qian
;
Gao, Lixin
;
Xu, Linhao
;
Han, Yubing
;
Cao, Yu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/12/11
Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 23, 页码: 21577-21616
作者:
Li, Junhua
;
Hu, Qingqing
;
Zhu, Run
;
Dong, Ruibo
;
Shen, Hui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/01/10
Aerial Image Segmentation of Nematode-Affected Pine Trees with U-Net Convolutional Neural Network
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2024, 卷号: 14, 期号: 12, 页码: 14
作者:
Shen, Jiankang
;
Xu, Qinghua
;
Gao, Mingyang
;
Ning, Jicai
;
Jiang, Xiaopeng
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/10/24
UAV remote sensing
pine wood nematode
machine learning
U-Net
Mitochondrial dynamic remodeling in strenuous exercise-induced muscle and rnitochondrial dysfunction: Regulatory effects of hydroxytyrosol
期刊论文
OAI收割
FREE RADICAL BIOLOGY AND MEDICINE, 2011, 卷号: 50, 期号: 10, 页码: 1437-1446
作者:
Feng, Zhihui
;
Bai, Liyuan
;
Yan, Jiong
;
Li, Yuan
;
Shen, Weili
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2015/08/25
Mitochondrial biogenesis
Autophagy
Oxidative stress
Apoptosis
JNK pathway
Erk1/2 pathway
Free radicals
Hydroxytyrosol protects against oxidative damage by simultaneous activation of mitochondrial biogenesis and phase ii detoxifying enzyme systems in retinal pigment epithelial cells
期刊论文
iSwitch采集
Journal of nutritional biochemistry, 2010, 卷号: 21, 期号: 11, 页码: 1089-1098
作者:
Zhu, Lu
;
Liu, Zhongbo
;
Feng, Zhihui
;
Hao, Jiejie
;
Shen, Weili
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/05/10
Hydroxytyrosol
Rpe cells
Acrolein
Amd
Mitochondrial biogenesis
Phase ii enzymes
Hydroxytyrosol promotes mitochondrial biogenesis and mitochondrial function in 3t3-l1 adipocytes
期刊论文
iSwitch采集
Journal of nutritional biochemistry, 2010, 卷号: 21, 期号: 7, 页码: 634-644
作者:
Hao, Jiejie
;
Shen, Weili
;
Yu, Guangli
;
Jia, Haiqun
;
Li, Xuesen
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/05/10
5 ' amp-activated protein kinase (ampk)
Fatty acid oxidation
Mitochondrial transcription factor a (tfam)
Mitochondrial dna (mtdna)
Nuclear respiration factors 1 and 2 (nrf1 and nrf2)
Peroxisome proliferator-activated receptor coactivator 1 alpha (ppargc1 alpha)
Synergistic anti-parkinsonism activity of high doses of b vitamins in a chronic cellular model
期刊论文
iSwitch采集
Neurobiology of aging, 2010, 卷号: 31, 期号: 4, 页码: 636-646
作者:
Jia, Haiqun
;
Liu, Zhongbo
;
Li, Xin
;
Feng, Zhihui
;
Hao, Jiejie
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/05/10
Mitochondrial membrane potential
Complex i
Reactive oxygen species
Oxidative dna damage
Protein carbonyl
Combined r-alpha-lipoic acid and acetyl-l-carnitine exerts efficient preventative effects in a cellular model of parkinson's disease
期刊论文
iSwitch采集
Journal of cellular and molecular medicine, 2010, 卷号: 14, 期号: 1-2, 页码: 215-225
作者:
Zhang, Hongyu
;
Jia, Haiqun
;
Liu, Jianghai
;
Ao, Ni
;
Yan, Bing
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/05/10
Lipoic acid
Acetyl-l-carnitine
Mitochondrial dysfunction
Oxidative damage
Parkinson's disease
Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic goto-kakizaki rats
期刊论文
iSwitch采集
Journal of cellular and molecular medicine, 2009, 卷号: 13, 期号: 4, 页码: 701-711
作者:
Hao, Jiejie
;
Shen, Weili
;
Tian, Chuan
;
Liu, Zhongbo
;
Ren, Jinmin
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/05/10
Alpha-lipoic acid
Acetyl-l-carnitine
Nicotinamide
Biotin
Oxidative damage
Mitochondrial dysfunction