中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [17]
国家天文台 [8]
近代物理研究所 [5]
计算技术研究所 [4]
宁波材料技术与工程研... [4]
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OAI收割 [103]
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期刊论文 [103]
预印本 [1]
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2025 [2]
2024 [6]
2023 [10]
2022 [5]
2021 [13]
2020 [5]
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Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 19
作者:
Yin, Wen
;
Xu, Heng
;
Bai, Zhonghao
;
Wu, Yue
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 12
作者:
He, Xin-heng
;
Li, Jun-rui
;
Shen, Shi-yi
;
Xu, H. Eric
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/01/14
AlphaFold
structure-based drug design
artificial intelligence
GPCR
structural biology
AI-driven antibody design with generative diffusion models: current insights and future directions
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 10
作者:
He, Xin-heng
;
Li, Jun-rui
;
Xu, James
;
Shan, Hong
;
Shen, Shi-yi
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/11/05
antibodies
generative model
diffusion
de novo antibody design
CDR optimization
model evaluation
Synthesis and biological evaluation of multimodal monoaminergic arylpiperazine derivatives with potential antidepressant profile
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 16
作者:
Zheng, Jiefang
;
Zhou, Liping
;
Gong, Xudong
;
Yang, Feipu
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Triple reuptake inhibitors
5-HT 1A R agonists
Antidepressants
Multimodal serotonergic compounds
Study of tree shrew biology and models: A booming and prosperous field for biomedical research
期刊论文
OAI收割
ZOOLOGICAL RESEARCH, 2024, 卷号: 45, 期号: 4, 页码: 877-909
作者:
Yao, Yong-Gang
;
Lu, Li
;
Ni, Rong-Jun
;
Bi, Rui
;
Chen, Ceshi
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/08/26
Tree shrew
Animal model
Neurodegenerative diseases
Infectious diseases
Neuroscience
Phenome
Penpulimab, an anti-PD-1 antibody, for heavily pretreated metastatic nasopharyngeal carcinoma: a single-arm phase II study
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9
作者:
Chen, Xiaozhong
;
Wang, Wei
;
Zou, Qingfeng
;
Zhu, Xiaodong
;
Lin, Qin
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/20
Medcheck: a novel software for automated de-formulation of traditional Chinese medicine (TCM) prescriptions by liquid chromatography-mass spectrometry
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 6, 页码: 3
作者:
Li, Xiao-lan
;
Zhang, Jian-qing
;
Li, Yun
;
Shen, Xuan-jing
;
Yang, Huan-ya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
High-Cycle Fatigue Properties and Life Prediction of ZK30 Magnesium Alloy at Room and Elevated Temperatures
期刊论文
OAI收割
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE, 2023, 页码: 9
作者:
Xu, Zikuan
;
Huang, Lixin
;
Liu, Rui
;
Zhan, Hongyi
;
Zhang, Peng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/08
fatigue life prediction
fatigue strength
high-cycle fatigue
high temperature
magnesium alloy