中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
化学研究所 [6]
昆明植物研究所 [2]
自动化研究所 [1]
采集方式
OAI收割 [21]
内容类型
期刊论文 [21]
发表日期
2025 [2]
2023 [1]
2022 [4]
2021 [2]
2020 [2]
2019 [2]
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学科主题
Endocrinol... [1]
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Clerodane diterpenoids from the vine stems of
Fibraurea
recisa
Pierre and their hepatic gluconeogenesis inhibitory activity
期刊论文
OAI收割
PHYTOCHEMISTRY, 2025, 卷号: 232, 页码: 12
作者:
Wang, Hai-Yin
;
Shen, Yu
;
Nie, Wei
;
Tu, Wen-Chao
;
Huang, Suling
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Fibraurea recisa Pi erre
Menispermaceae
Clerodane diterpenoids
Hepatic gluconeogenesis
Diabetes mellitus
Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 15
作者:
Yu, Nai-Rong
;
Huang, Suling
;
Deng, Zhen-Tao
;
Wang, Jiayue
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Non-alcoholic steatohepatitis (NASH)
Alisol B
Structural modification
Structure-activity relationship
HFD+CCl4-induced NASH mice model
Phenotypic screening-based drug discovery of furan-2-carboxylic acid derivatives for the amelioration of type 2 diabetes mellitus (T2DM)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 246, 页码: 11
作者:
Chen, Lili
;
Huang, Suling
;
Ye, Yangliang
;
Shen, Yu
;
Xu, Tifei
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Phenotypic screening
Gluconeogenesis
Furan-2-carboxylic acid
T2DM
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 20
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/08/16
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
Design, synthesis and structural-activity relationship studies of phanginin A derivatives for regulating SIK1-cAMP/CREB signaling to suppress hepatic gluconeogenesis
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 232, 页码: 14
作者:
Wu, Xing-De
;
Huang, Suling
;
Shi, Yu
;
Shen, Yu
;
Tu, Wen-Chao
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/08/16
Hepatic gluconeogenesis
Type 2 diabetes
Phanginin A derivatives
SIK1
Structural-activity relationship
Development and structure-activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
NATURAL PRODUCTS AND BIOPROSPECTING, 2022, 卷号: 12, 期号: 6, 页码: 1
作者:
Deng Xu
;
Huang Suling
;
Ren Jian
;
Pan Zhenghong
;
Shen Yu
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/05/22
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure-activity relationships
Alisol B Alleviates Hepatocyte Lipid Accumulation and Lipotoxicity via Regulating RAR alpha-PPAR gamma-CD36 Cascade and Attenuates Non-Alcoholic Steatohepatitis in Mice
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 12, 页码: 2411
作者:
Zhao, Zhuohui
;
Deng, Zhen-Tao
;
Huang, Suling
;
Ning, Mengmeng
;
Feng, Ying
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/04/30
Alisol B
non-alcoholic steatohepatitis
RAR alpha
CD36
FATTY LIVER
HEPATIC STEATOSIS
RECEPTOR
ORIENTALE
LIPOPROTEINS
23-ACETATE
AGONIST
CD36
Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK
期刊论文
OAI收割
CLINICAL SCIENCE, 2021, 卷号: 135, 期号: 19, 页码: 2243-2263
作者:
Elksnis, Andris
;
Schiffer, Tomas A.
;
Palm, Fredrik
;
Wang, Yun
;
Cen, Jing
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/12/01
An integrative drug repositioning framework discovered a potential therapeutic agent targeting COVID-19
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 16
作者:
Ge, Yiyue
;
Tian, Tingzhong
;
Huang, Suling
;
Wan, Fangping
;
Li, Jingxin
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2022/06/15
Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
期刊论文
OAI收割
MOLECULAR METABOLISM, 2020, 卷号: 41, 页码: 15
作者:
Liu, Siwen
;
Huang, Suling
;
Wu, Xingde
;
Feng, Ying
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
Salt-inducible kinase 1
Phanginin A
Phosphodiesterase 4
Gluconeogenesis
cAMP