中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
地理科学与资源研究所 [7]
广州地球化学研究所 [3]
地球环境研究所 [2]
遥感与数字地球研究所 [1]
南京地理与湖泊研究所 [1]
更多
采集方式
OAI收割 [24]
内容类型
期刊论文 [24]
发表日期
2024 [3]
2023 [3]
2021 [4]
2020 [3]
2019 [5]
2017 [1]
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学科主题
Biology [1]
Ecology [1]
Evolutiona... [1]
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共24条,第1-10条
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Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:
Zhong, Ye
;
Xu, Jing
;
Ding, Shaoyue
;
Cao, Huiying
;
Zhang, Yufei
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/08/22
CDK9
Inhibitor
Colorectal cancer
Apoptosis
Tridentate ligand
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
Zhong, Ye
;
Xu, Jing
;
Zhou, Ruochen
;
Tang, Li
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/05/07
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
;
Li, Lingyun
;
Sun, Yili
;
Meng, Xiangjing
;
Shi, Zhenzhong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 13
作者:
Xu, Yanhong
;
Ye, Xiaotong
;
Zhou, Yang
;
Cao, Xinyu
;
Peng, Shiqiao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/04/10
sodium butyrate
succinylation
HMGCS2
ketogenesis
SIRT5
Vertical distribution changes in land cover between 1990 and 2015 within the Koshi River Basin, Central Himalayas
期刊论文
OAI收割
JOURNAL OF GEOGRAPHICAL SCIENCES, 2021, 卷号: 31, 期号: 10, 页码: 1419-1436
作者:
Wu Xue
;
Paudel Basanta
;
Zhang Yili
;
Liu Linshan
;
Wang Zhaofeng
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/11/05
vertical belt
land cover
Central Himalayas
Koshi River Basin
climate change
Vertical distribution changes in land cover between 1990 and 2015 within the Koshi River Basin, Central Himalayas
期刊论文
OAI收割
JOURNAL OF GEOGRAPHICAL SCIENCES, 2021, 卷号: 31, 期号: 10, 页码: 1419-1436
作者:
Wu Xue
;
Paudel Basanta
;
Zhang Yili
;
Liu Linshan
;
Wang Zhaofeng
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/11/05
vertical belt
land cover
Central Himalayas
Koshi River Basin
climate change
Application of XRF Scanning to Different Geological Archives
期刊论文
OAI收割
EARTH AND SPACE SCIENCE, 2021, 卷号: 8, 期号: 9, 页码: 20
作者:
Guo, Fei
;
Clemens, Steven
;
Liu, Xingxing
;
Long, Yili
;
Li, Dong
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/12/07
XRF scanning analytical method
loess
stalagmite
tridacna
paleoclimate
Species packing and the latitudinal gradient in beta-diversity
期刊论文
OAI收割
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2021, 卷号: 288, 期号: 1948
作者:
Cao, Ke
;
Condit, Richard
;
Mi, Xiangcheng
;
Chen, Lei
;
Ren, Haibao
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/02/24
beta-diversity
gamma-diversity
sampling bias
latitude
species packing
niche specialization