中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
地理科学与资源研究所 [7]
广州地球化学研究所 [3]
地球环境研究所 [2]
遥感与数字地球研究所 [1]
南京地理与湖泊研究所 [1]
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采集方式
OAI收割 [28]
内容类型
期刊论文 [28]
发表日期
2025 [4]
2024 [3]
2023 [3]
2021 [4]
2020 [3]
2019 [5]
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Biology [1]
Ecology [1]
Evolutiona... [1]
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浏览/检索结果:
共28条,第1-10条
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The deubiquitinase USP2 preserves intestinal barrier through the TRAF6/ NF-κB/MLCK/MLC signaling in ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2025, 卷号: 162, 页码: 12
作者:
Zhou, Ruochen
;
Cui, Yuanyuan
;
Wang, Weihao
;
Qu, Yidan
;
Zhang, Gaojie
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Ubiquitin-specific protease 2
Ulcerative colitis
Intestinal epithelial cell
Tight junction
First ATG101-recruiting small molecule degrader for selective CDK9 degradation
via
autophagy-lysosome pathway
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624
作者:
Zhong, Ye
;
Xu, Jing
;
Cao, Huiying
;
Gao, Jie
;
Ding, Shaoyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
Protein degradation
Hydrophobic tags
ATG101
Autophagy-lysosome pathway
CDK9
Cyclin T1
Degrader
Antitumor
Divergent Synthesis of Dihydrofuran and Dienol Scaffolds via Pd-Catalyzed Decarboxylative Carbene Cross-Coupling
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 18, 页码: 4753-4761
作者:
Ma, Xiaolong
;
Miao, Erfei
;
Sun, Yili
;
Sun, Longkang
;
Huang, Chaoying
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/06/23
Apigenin alleviates inflammation as a natural IRAK4 inhibitor
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 139, 页码: 12
作者:
Gongpan, Pianchou
;
Xu, Tingting
;
Zhang, Yufei
;
Ji, Kailong
;
Kong, Lingmei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/04/24
Apigenin
IRAK4 inhibitor
Anti-inflammation
NF-kappa B
MAPK pathways
Ulcerative colitis
Discovery of novel CDK9 inhibitor with tridentate ligand: Design, synthesis and biological evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 150, 页码: 12
作者:
Zhong, Ye
;
Xu, Jing
;
Ding, Shaoyue
;
Cao, Huiying
;
Zhang, Yufei
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2024/08/22
CDK9
Inhibitor
Colorectal cancer
Apoptosis
Tridentate ligand
Discovery and Optimization of Novel Nonbile Acid FXR Agonists as Preclinical Candidates for the Treatment of Inflammatory Bowel Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 7, 页码: 5642-5661
作者:
Li, Yuan
;
Xu, Tingting
;
Zhao, Yue
;
Zhang, Hui
;
Liu, Zesheng
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/05/07
Identification of a Novel Selective CDK9 Inhibitor for the Treatment of CRC: Design, Synthesis, and Biological Activity Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 6, 页码: 4739-4756
作者:
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/05/07
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
;
Li, Lingyun
;
Sun, Yili
;
Meng, Xiangjing
;
Shi, Zhenzhong
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
Sodium butyrate activates HMGCS2 to promote ketone body production through SIRT5-mediated desuccinylation
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 13
作者:
Xu, Yanhong
;
Ye, Xiaotong
;
Zhou, Yang
;
Cao, Xinyu
;
Peng, Shiqiao
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2023/04/10
sodium butyrate
succinylation
HMGCS2
ketogenesis
SIRT5