中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [29]
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期刊论文 [100]
会议论文 [2]
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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Identification of Cannabigerol-Derived Dual CB
2
Receptor Agonists and TRPM8 Antagonists with Anti-Inflammatory and Analgesic Activities
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 13, 页码: 13335-13357
作者:
Yang, Wenjiao
;
Sun, Haiguo
;
Ji, Jing
;
Chen, Hai
;
Cheng, Jiaxin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Design and Development of a Novel Oral 4′-Fluorouridine Double Prodrug VV261 against SFTSV
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 9, 页码: 9811-9826
作者:
Cheng, Yong
;
Zheng, Wei
;
Dong, Xinru
;
Sun, Tengxiao
;
Xu, Mengwei
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/06/23
Discovery of peptidomimetic spiropyrrolidine derivatives as novel 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 281, 页码: 22
作者:
Guma, Samuel Desta
;
Zhou, Zhaoyin
;
Song, Kang
;
Yang, Feipu
;
Suo, Jin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/11
SARS-CoV-2
3CL pro inhibitors
Peptidomimetics
Spiropyrrolidine derivatives
Determining the priority control sources of heavy metals in the roadside soils in a typical industrial city of North China
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2024, 卷号: 480, 页码: 136347
作者:
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/12/20
Heavy metals
Roadside soils
Monte Carlo simulation
Random forest
Positive matrix factorization
Sequential Scan-Based High-Resolution 3-D Open-Sided Magnetic Particle Imaging System
期刊论文
OAI收割
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2024, 卷号: 73, 页码: 12
作者:
He, Jie
;
Zhang, Haoran
;
Lei, Siao
;
Li, Guanghui
;
Li, Yimeng
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/07/22
Coils
Permanent magnets
Motors
Superparamagnetic iron oxide nanoparticles
Spatial resolution
Magnetic fields
Interference
Field-free line (FFL)
magnetic particle imaging (MPI)
open-sided
sequential scan
Modified Jiles-Atherton Model-Based System Matrix Generation Method for Magnetic Particle Imaging
期刊论文
OAI收割
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT, 2024, 卷号: 73, 页码: 9
作者:
Li, Yimeng
;
Li, Guanghui
;
Zhang, Peng
;
An, Yu
;
Hui, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/07/03
Coils
Magnetization
Electromagnetics
Image reconstruction
Voltage measurement
Mathematical models
Biomedical imaging
Magnetic nanoparticle
magnetic particle imaging (MPI)
modified Jiles-Atherton (MJA) model
system matrix (SM)
Progressive Pretraining Network for 3D System Matrix Calibration in Magnetic Particle Imaging
期刊论文
OAI收割
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2023, 卷号: 42, 期号: 12, 页码: 3639-3650
作者:
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/02/22
Magnetic particle imaging
system matrix
multimodal data
pretraining strategy
Weighted sum of harmonic signals for direct imaging in magnetic particle imaging
期刊论文
OAI收割
PHYSICS IN MEDICINE AND BIOLOGY, 2023, 卷号: 68, 期号: 1, 页码: 13
作者:
Liu, Yanjun
;
Hui, Hui
;
Liu, Sijia
;
Li, Guanghui
;
Zhang, Bo
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2023/02/22
magnetic particle imaging
short-time fourier transform
direct imaging
multi-patch imaging