机构

• 上海药物研究所 [53]

采集方式

• OAI收割 [53]

内容类型

• 期刊论文 [51]
• 会议论文 [2]

发表日期

• 2023 [1]
• 2022 [1]
• 2019 [2]
• 2018 [2]
• 2017 [6]
• 2016 [5]
• 更多

学科主题

筛选

浏览/检索结果: 共53条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16 作者:  He, Yulong;  Li, Shunyi;  Zhu, Yueyue;  Wang, Yujie;  Chen, Yuqi   |  收藏  |  浏览/下载：64/0  |  提交时间：2023/10/17 Structure-activity relationship  FABP4 inhibitor  Biphenyl scaffold  Selectivity  Oral bioavailability  Anti-inflammation   Roles of hydroxyeicosatetraenoic acids in diabetes (HETEs and diabetes) 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2022, 卷号: 156, 页码: 13 作者:  Dong, Linyue;  Wang, Heyao;  Chen, Kaixian;  Li, Yiming   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/04/10 5-HETE  12-HETE  15-HETE  20-HETE  Lipoxygenases  Diabetes  Obesity   Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16 作者:  He, Yulong;  Dou, Huixia;  Gao, Dingding;  Wang, Ting;  Zhang, Mingming   |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 Dual FABP4/5 inhibitor  Structure-based design  Lipolysis inhibition  Anti-inflammatory effects   Vincamine as a GPR40 agonist improves glucose homeostasis in type 2 diabetic mice 期刊论文  OAI收割 JOURNAL OF ENDOCRINOLOGY, 2019, 卷号: 240, 期号: 2, 页码: 195-214 作者:  Du, Te;  Yang, Liu   |  收藏  |  浏览/下载：102/0  |  提交时间：2019/01/08 vincamine  GPR40  beta-cell function  insulin secretion  type 2 diabetes   Enhancement of Berberine Hypoglycemic Activity by Oligomeric Proanthocyanidins 期刊论文  OAI收割 Molecules (Basel, Switzerland), 2018, 卷号: 23, 期号: 12 作者:  Zhang, Haoyue;  Wang, Xueping;  Wang, Ting;  Chen, Kaixian;  Wang, Heyao   |  收藏  |  浏览/下载：77/0  |  提交时间：2019/01/08 Discovery of novel selective GPR120 agonists with potent anti-diabetic activity by hybrid design 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 15, 页码: 2599-2604 作者:  Sheng, Ren;  Yang, Liu;  Zhang, Yanchun;  Xing, Enming;  Shi, Rui   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 GPR120  Agonist biphenyl derivatives  OGTT  Type 2 diabetes   Discovery of a low-systemic-exposure DGAT-1 inhibitor with a picolinoylpyrrolidine-2-carboxylic acid moiety 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 17, 页码: 4701-4714 作者:  Yan, Jianwei;  Wang, Gaihong;  Dang, Xiangyu;  Guo, Binbin;  Chen, Wuhong   |  收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 DGAT-1  Inhibitor  Triglyceride  Hyperlipidemia   A Novel Sarsolenane Diterpene as a PTP1B Inhibitor from Hainan Soft Coral Sarcophyton trocheliophorum Marenzeller 期刊论文  OAI收割 CHINESE JOURNAL OF CHEMISTRY, 2017, 卷号: 35, 期号: 8, 页码: 1246-1250 作者:  Liang, Linfu;  Wang, Jinan;  Shi, Xiaoxuan;  Zhu, Yinghua;  Li, Jia   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Sarcophyton trocheliophrum  sarsolenane  structure elucidation  PTP1B inhibitory activity  binding mode   Docking-based structural splicing and reassembly strategy to develop novel deazapurine derivatives as potent B-Raf~(V600E) inhibitors 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 7, 页码: 1057-1068 作者:  Wang Guimin;  Wang Xiang;  Zhu Jianming;  Guo Binbin;  Yang Zhuo   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 B-Raf~(V600E) inhibitor  anticancer  vemurafenib  deazapurine  fragment reassembly  molecular docking  structure-activity relationship   anovelsarsolenanediterpeneasaptp1binhibitorfromhainansoftcoralsarcophytontrocheliophorummarenzeller 期刊论文  OAI收割 chinesejournalofchemistry, 2017, 卷号: 35, 期号: 8, 页码: 1246 作者:  Liang Linfu   |  收藏  |  浏览/下载：8/0  |  提交时间：2020/07/01 Sarcophyton trocheliophrum  sarsolenane  structure elucidation  PTP1B inhibitory activity  binding mode