中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
广州生物医药与健康研... [1]
合肥物质科学研究院 [1]
昆明动物研究所 [1]
采集方式
OAI收割 [13]
内容类型
期刊论文 [12]
学位论文 [1]
发表日期
2024 [1]
2023 [1]
2021 [2]
2020 [1]
2019 [1]
2015 [1]
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学科主题
药物化学 [1]
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Structure-based design of potent FABP4 inhibitors with high selectivity against FABP3
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 10
作者:
Chen, Guofeng
;
Xie, Hang
;
Liu, Jiayuan
;
Shao, Qiang
;
Li, Minjun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
Methyl substitution
Selectivity
FABP4 inhibitor
Anti-inflammation
Metabolic stability
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:
He, Yulong
;
Li, Shunyi
;
Zhu, Yueyue
;
Wang, Yujie
;
Chen, Yuqi
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/17
Structure-activity relationship
FABP4 inhibitor
Biphenyl scaffold
Selectivity
Oral bioavailability
Anti-inflammation
Aurora Kinase A as a Diagnostic and Prognostic Marker of Malignant Mesothelioma
期刊论文
OAI收割
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
作者:
Guo, Zhenying
;
Shen, Li
;
Li, Ningning
;
Wu, Xiaoxiao
;
Wang, Canming
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/01/25
malignant mesothelioma
bioinformatics
biomarkers
tissue microarray
Aurora kinase A
Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice
期刊论文
OAI收割
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 页码: 10
作者:
Chen, Meng-Ting
;
Huang, Jun-Shang
;
Gao, Ding-Ding
;
Li, Ying-Xia
;
Wang, He-Yao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
combined treatment
FABP4 inhibitor
liver steatosis
obese type 2 diabetes
rosiglitazone
Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes
期刊论文
OAI收割
ENDOCRINE, 2020, 卷号: 67, 期号: 3, 页码: 587-596
作者:
Dou, Hui-Xia
;
Wang, Ting
;
Su, Hai-Xia
;
Gao, Ding-Ding
;
Xu, Ye-Chun
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
eFABP4
Adipocyte
Differentiation
Lipolysis
Inflammation
Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16
作者:
He, Yulong
;
Dou, Huixia
;
Gao, Dingding
;
Wang, Ting
;
Zhang, Mingming
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
Dual FABP4/5 inhibitor
Structure-based design
Lipolysis inhibition
Anti-inflammatory effects
Novel fatty acid binding protein 4 (FABP4) inhibitors: Virtual screening, synthesis and crystal structure determination
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 241-250
作者:
Cai, Haiyan
;
Liu, Qiufeng
;
Gao, Dingding
;
Wang, Ting
;
Chen, Tiantian
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
FABP4
Inhibitor
Diabetes
Virtual screening
Crystal structure
Small Molecule Inhibitors of Human Adipocyte Fatty Acid Binding Protein (FABP4)
期刊论文
OAI收割
MEDICINAL CHEMISTRY, 2014, 卷号: 10, 期号: 4, 页码: 339-347
作者:
Zhang, Mingming
;
Zhu, Weiliang
;
Li, Yingxia
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Fatty acid binding protein 4
FABP4
inhibitor
receptor
small molecule
type 2 diabetes
Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 1397-1402
作者:
Cai, Hai-yan
;
Wang, Ting
;
Zhao, Jian-chun
;
Sun, Peng
;
Yan, Gui-rui
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
benzbromarone
uricosuric drug
fatty acid-binding protein 4
adipocyte
diabetes
db/db mouse
molecular docking
Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2013, 卷号: 436, 期号: 2, 页码: 169-174
作者:
He YH
;
Li Y
;
Zhang SC
;
Perry B
;
Zhao TT
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2013/08/30
Radicicol
Differentiation
Heat shock protein
Adipocytes