机构

• 化学研究所 [24]
• 上海药物研究所 [13]
• 合肥物质科学研究院 [4]
• 武汉物理与数学研究所 [3]
• 中国科学院大学 [3]
• 宁波材料技术与工程研... [2]
• 更多

采集方式

• OAI收割 [51]
• iSwitch采集 [3]

内容类型

• 期刊论文 [53]
• 会议论文 [1]

发表日期

• 2025 [3]
• 2024 [4]
• 2023 [2]
• 2022 [4]
• 2021 [5]
• 2019 [4]
• 更多

学科主题

• Chemistry [1]

筛选

浏览/检索结果: 共54条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Structure-activity relationship analysis of meta-substituted N-cyclopropylmethyl-nornepenthones with mixed KOR/MOR activities 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 15 作者:  Tang, Siyuan;  Hu, Shuyang;  Feng, Lijing;  Kong, Linghui;  Gui, Jiangwen   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/05/27 N-Cyclopropylmethyl-nornepenthones  Structure-activity relationship  MOR antagonist  KOR agonist  Substance use disorder   IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response 期刊论文  OAI收割 EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19 作者:  Yao, Mingyue;  Yan, Wenzhong;  Wang, Yafang;  Zhao, Yu;  Xu, Xiaowei   |  收藏  |  浏览/下载：9/0  |  提交时间：2025/04/01 Acute myeloid leukemia  HDAC inhibitor  FLT3-ITD mutation  DNA damage response  Synergistic effect  Drug resistance   Rapid identification method for on-road high-emission vehicle based on deep semi-supervised anomaly detection 期刊论文  OAI收割 MEASUREMENT, 2025, 卷号: 239 作者:  Han, Lingran   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/11/20 High-emission vehicle identification  Data fusion  Deep anomaly detection  Semi-supervised learning  The chassis and engine dynamometer testing  On-road remote sensing system   Ammonia emission concentration measurement using laser absorption spectroscopy chamber system based on deep belief networks 期刊论文  OAI收割 OPTICAL ENGINEERING, 2024, 卷号: 63 作者:  Yu, Dongqi   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/11/20 ammonia measurement  deep belief network  gas concentration retrieval  tunable diode laser absorption spectroscopy   Quantifying gas emissions through Vertical Radial Plume Mapping based on historical information 期刊论文  OAI收割 MEASUREMENT, 2024, 卷号: 234 作者:  Zhang, Wangchun;  Zhang, Yujun;  He, Ying;  You, Kun;  Xie, Hao   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/11/20 Vertical Radial Plume Mapping  Weighted Iterative Average  Adaptive Weighted Sum of Squared Errors  Bayesian Optimization Gaussian Processes  Historical information   Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36 作者:  Lou, Jianfeng;  Zhou, Qianqian;  Lyu, Xilin;  Cen, Xinyi;  Liu, Chen   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/08/22 Discovery of an Ortho-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129 作者:  Li, Zixiang;  Ye, Rufeng;  He, Qian;  Lu, Jiashuo;  Sun, Yanting   |  收藏  |  浏览/下载：29/0  |  提交时间：2024/06/27 Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15 作者:  Kong, Linghui;  Ning, Kuan;  Liu, Xiao;  Lu, Jiashuo;  Chen, Baiyu   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/10/17 N-cyclopropylmethyl nornepenthone derivatives  derivatives  Structure-activity relationship  MOR antagonist  Functional reversal  Reversal of subtype-selectivity  Opioid use disorder   PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173 作者:  Sun, Mingming;  Li, Leilei;  Niu, Yujia;  Wang, Yingzhi;  Yan, Qi   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/03/27 Lung cancer  Metabolic reprogramming  Post-translational modification  PRMT6  Pentose phosphate pathway flux  Glycolysis  6-Phospho-gluconate dehydrogenase  a-enolase  ENO1   SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16 作者:  Kong, Linghui;  Shu, Xuelian;  Tang, Siyuan;  Ye, Rongrong;  Sun, Huijiao   |  收藏  |  浏览/下载：63/0  |  提交时间：2022/08/30