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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
化学研究所 [24]
上海药物研究所 [12]
合肥物质科学研究院 [4]
武汉物理与数学研究所 [3]
中国科学院大学 [3]
宁波材料技术与工程研... [2]
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OAI收割 [50]
iSwitch采集 [3]
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期刊论文 [52]
会议论文 [1]
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2025 [2]
2024 [4]
2023 [2]
2022 [4]
2021 [5]
2019 [4]
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Chemistry [1]
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IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:
Yao, Mingyue
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Acute myeloid leukemia
HDAC inhibitor
FLT3-ITD mutation
DNA damage response
Synergistic effect
Drug resistance
Rapid identification method for on-road high-emission vehicle based on deep semi-supervised anomaly detection
期刊论文
OAI收割
MEASUREMENT, 2025, 卷号: 239
作者:
Han, Lingran
;
Zhang, Yujun
;
He, Ying
;
You, Kun
;
Liu, Wenqing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/11/20
High-emission vehicle identification
Data fusion
Deep anomaly detection
Semi-supervised learning
The chassis and engine dynamometer testing
On-road remote sensing system
Ammonia emission concentration measurement using laser absorption spectroscopy chamber system based on deep belief networks
期刊论文
OAI收割
OPTICAL ENGINEERING, 2024, 卷号: 63
作者:
Yu, Dongqi
;
Zhang, Yujun
;
He, Ying
;
You, Kun
;
Fan, Boqiang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/11/20
ammonia measurement
deep belief network
gas concentration retrieval
tunable diode laser absorption spectroscopy
Quantifying gas emissions through Vertical Radial Plume Mapping based on historical information
期刊论文
OAI收割
MEASUREMENT, 2024, 卷号: 234
作者:
Zhang, Wangchun
;
Zhang, Yujun
;
He, Ying
;
You, Kun
;
Xie, Hao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/11/20
Vertical Radial Plume Mapping
Weighted Iterative Average
Adaptive Weighted Sum of Squared Errors
Bayesian Optimization Gaussian Processes
Historical information
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Lou, Jianfeng
;
Zhou, Qianqian
;
Lyu, Xilin
;
Cen, Xinyi
;
Liu, Chen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/08/22
Discovery of an Ortho-Substituted
N
-Cyclopropylmethyl-7α-phenyl-6,14-
endo
ethano-tetrahydronorthebaine Derivative as a Selective and Potent Kappa Opioid Receptor Agonist with Subsided Sedative Effect
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 9, 页码: 7112-7129
作者:
Li, Zixiang
;
Ye, Rufeng
;
He, Qian
;
Lu, Jiashuo
;
Sun, Yanting
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/06/27
Reversal of subtype-selectivity and function by the introduction of a para-benzamidyl substituent to N-cyclopropylmethyl nornepenthone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 15
作者:
Kong, Linghui
;
Ning, Kuan
;
Liu, Xiao
;
Lu, Jiashuo
;
Chen, Baiyu
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/10/17
N-cyclopropylmethyl nornepenthone derivatives
derivatives
Structure-activity relationship
MOR antagonist
Functional reversal
Reversal of subtype-selectivity
Opioid use disorder
PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 1, 页码: 157-173
作者:
Sun, Mingming
;
Li, Leilei
;
Niu, Yujia
;
Wang, Yingzhi
;
Yan, Qi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/27
Lung cancer
Metabolic reprogramming
Post-translational modification
PRMT6
Pentose phosphate pathway flux
Glycolysis
6-Phospho-gluconate dehydrogenase
a-enolase
ENO1
SLL-627 Is a Highly Selective and Potent ? Opioid Receptor (KOR) Agonist with an Unexpected Nonreduction in Locomotor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 16
作者:
Kong, Linghui
;
Shu, Xuelian
;
Tang, Siyuan
;
Ye, Rongrong
;
Sun, Huijiao
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2022/08/30
Coupled Simulation of Hydrate-Bearing and Overburden Sedimentary Layers to Study Hydrate Dissociation and Methane Leakage
期刊论文
OAI收割
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2022, 卷号: 10, 期号: 5, 页码: 19
作者:
Xie, Yan
;
Feng, Jingchun
;
Sun, Liwei
;
Wang, Junwen
;
Hu, Weiqiang
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/11/21
natural gas hydrate
methane leakage
CH4 hydrate dissociation
simulator
dynamic separation