中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
高能物理研究所 [37]
近代物理研究所 [22]
上海药物研究所 [18]
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期刊论文 [169]
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
PM
2.5
-mediated cardiovascular disease in aging: Cardiometabolic risks, molecular mechanisms and potential interventions
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 卷号: 954, 页码: 22
作者:
Chanda, Francis
;
Lin, Kai-xuan
;
Chaurembo, Abdallah Iddy
;
Huang, Jian-yuan
;
Zhang, Hui-juan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/11/05
PM2.5
Cardiovascular disease
Cardiometabolic risk
Older adults
Inflammation
Oxidative stress
Oxidative stress
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Salmonella
Biomimetic Nanoparticles for Photothermal-Chemotherapy of Colorectal Cancer
期刊论文
OAI收割
NANO LETTERS, 2024, 卷号: 24, 期号: 43, 页码: 13851-13860
作者:
Liu, Ruichi
;
Miao, Yunqiu
;
Wen, Keyi
;
Yang, Yang
;
Xu, Dan
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/11/26
colorectal cancer
salmonella biomimetic nanoparticles
photothermal-chemotherapy
tumor targeting
tumor penetration
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/06/29
Mitofilin in cardiovascular diseases: Insights into the pathogenesis and potential pharmacological interventions
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2024, 卷号: 203, 页码: 20
作者:
Chaurembo, Abdallah Iddy
;
Xing, Na
;
Chanda, Francis
;
Li, Yuan
;
Zhang, Hui-juan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/06/27
Mitofilin
Cristae junction
Mitochondrial dysfunction
Cardiovascular diseases
Mitochondrial-targeted therapy
Multiple heart-cutting two-dimensional liquid chromatography/charged aerosol detector assay of ginsenosides for quality evaluation of ginseng from diverse Chinese patent medicines
期刊论文
OAI收割
JOURNAL OF CHROMATOGRAPHY A, 2023, 卷号: 1708, 页码: 10
作者:
Xu, Xiao-yan
;
Jiang, Mei-ting
;
Wang, Yu
;
Sun, He
;
Jing, Qi
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/12/08
Multiple heart -cutting two-dimensional liquid
chromatography
Charged aerosol detector
Quantitative assay
Ginseng
Chinese patent medicine
Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial
期刊论文
OAI收割
LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13
作者:
Wang, Fuxiang
;
Xiao, Wen
;
Tang, Yimin
;
Cao, Mengli
;
Shu, Dan
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
Covid-19
3CL protease inhibitor
SARS-CoV-2 viral load
Alleviation of COVID-19 symptoms
A longitudinal resource for population neuroscience of school-age children and adolescents in China
期刊论文
OAI收割
SCIENTIFIC DATA, 2023, 卷号: 10, 期号: 1, 页码: 24
作者:
Fan, Xue-Ru
;
Wang, Yin-Shan
;
Chang, Da
;
Yang, Ning
;
Rong, Meng-Jie
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2023/12/11
Comparative Characterization of the Ginsenosides from Six Panax Herbal Extracts and Their In Vitro Rat Gut Microbial Metabolites by Advanced Liquid Chromatography-Mass Spectrometry Approaches
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 71, 期号: 24, 页码: 9391-9403
作者:
Mi, Yue-Guang
;
Xu, Xiao-Yan
;
Hong, Li-Li
;
Jiang, Mei-Ting
;
Chen, Bo-Xue
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17
Panax
multicomponent characterization
quantitative assay
gut microbiota
in vitro biotransformation
liquid chromatography-massspectrometry